Individualizing post-ICU nutrition: from guideline intent to bedside practice

Purpose of review Survivorship of critical illness has increased, shifting attention toward recovery and long-term outcomes. Post-ICU nutrition is emerging as a clinically relevant, yet underperforming contributor to functional recovery and quality of life. Persistent nutritional inadequacy reflects insufficiently defined physiological requirements and limited implementable evidence-based guidance during ICU recovery. Recent findings Energy and protein delivery sharply decline after ICU discharge, despite persistent metabolic demands. Underfeeding can result from the absence of recovery-specific targets, patient-level barriers (e.g. appetite loss, dysphagia, fatigue), and fragmented care transitions, including premature feeding-tube removal and suboptimal monitoring of oral intake. Structured patient and family engagement can help operationalize individualized nutritional strategies and improve feasibility without substantial resource burden, acting as continuity agents. Summary Post-ICU nutritional failure reflects combined physiological and implementation challenges. Clinicians should recognize the post-ICU hospitalization period as a potential ‘metabolic danger zone’, requiring a shift from acute-phase restrictive feeding toward strategies prioritizing functional recovery and lean mass preservation. Improving outcomes requires standardized, yet adaptable, care pathways that bridge ICU-to-ward transitions, operationalize individualization, and integrate patient and family input as clinical instruments. Future research should prioritize multicenter implementation studies centered on ‘disability-free survival’ to inform adaptive, evidence-based nutritional protocols.

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Publication Details

Journal
Current Opinion in Critical Care
Published
2026-07-22
DOI
https://doi.org/10.1097/mcc.0000000000001412
Primary Topic
Clinical Nutrition and Gastroenterology
Type
article
Field-Weighted Citation Impact
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article

Individualizing post-ICU nutrition: from guideline intent to bedside practice

Zenzi Rosseel, Claude Pichard, Arthur R. H. van Zanten, Lee‐anne S. Chapple et al.
Current Opinion in Critical Care
Clinical Nutrition and Gastroenterology
article

Individualizing post-ICU nutrition: from guideline intent to bedside practice

Zenzi Rosseel, Claude Pichard, Arthur R. H. van Zanten, Lee‐anne S. Chapple, Lu Ke, Dan Waitzberg, Krista Haines, Oona Leemans, Paul Wischmeyer, Elisabeth De Waele
article en

Abstract

Purpose of review Survivorship of critical illness has increased, shifting attention toward recovery and long-term outcomes. Post-ICU nutrition is emerging as a clinically relevant, yet underperforming contributor to functional recovery and quality of life. Persistent nutritional inadequacy reflects insufficiently defined physiological requirements and limited implementable evidence-based guidance during ICU recovery. Recent findings Energy and protein delivery sharply decline after ICU discharge, despite persistent metabolic demands. Underfeeding can result from the absence of recovery-specific targets, patient-level barriers (e.g. appetite loss, dysphagia, fatigue), and fragmented care transitions, including premature feeding-tube removal and suboptimal monitoring of oral intake. Structured patient and family engagement can help operationalize individualized nutritional strategies and improve feasibility without substantial resource burden, acting as continuity agents. Summary Post-ICU nutritional failure reflects combined physiological and implementation challenges. Clinicians should recognize the post-ICU hospitalization period as a potential ‘metabolic danger zone’, requiring a shift from acute-phase restrictive feeding toward strategies prioritizing functional recovery and lean mass preservation. Improving outcomes requires standardized, yet adaptable, care pathways that bridge ICU-to-ward transitions, operationalize individualization, and integrate patient and family input as clinical instruments. Future research should prioritize multicenter implementation studies centered on ‘disability-free survival’ to inform adaptive, evidence-based nutritional protocols.

Current Opinion in Critical Care
Royal Adelaide Hospital (AU), Vrije Universiteit Brussel (BE), Duke University (US), Universidade de São Paulo (BR), University Hospital of Geneva (CH), TiFN (NL), Ziekenhuis Gelderse Vallei (NL), Duke Medical Center (US), Universitair Ziekenhuis Brussel (BE), Jinling Institute of Technology (CN), The University of Adelaide (AU), Nanjing University (CN), Wageningen University & Research (NL)
Zero hunger
Openalex Percentile: Top 10%
Clinical Nutrition and Gastroenterology
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