Life-Space Mobility Trajectories After Elective Surgery in Older Adults

Importance: The number of older adults living with frailty who undergo surgery is rapidly increasing worldwide. Life-space mobility (LSM) can capture physical and social dimensions of recovery and has been linked to functional decline and reduced quality of life. Objective: To examine postoperative recovery using LSM among older adults living with frailty and to identify factors associated with restricted mobility and readmission. Design, Setting, and Participants: This cohort study within the larger Functional Improvement Trajectories After Surgery study used a convergent mixed-methods exploratory design. Seventeen hospitals across Canada included older adults aged 65 years or older with a clinical frailty score (CFS) of 3 or more who underwent major elective noncardiac surgery from March 2021 to June 2023. Data were analyzed from September to October 2025. Exposure: Elective noncardiac surgery among older adults. Main Outcomes and Measures: LSM (range 0-120, with higher scores indicating more mobility) was measured at 1 to 2 months and 6 months postoperatively, with retrospective presurgery LSM captured at 1 to 2 months. Multivariable linear mixed-effects models and multivariable mixed-effects logistic regression were used to identify factors associated with LSM trajectories, restricted mobility (ie, LSM < 60), and hospital readmission. Results: This study included 204 participants (mean [SD] age, 72.8 [5.6] years; 108 males [53%]). The mean (SD) LSM was 65.1 (26.7) presurgery, 56.6 (26.7) at 2 months postsurgery, and 64.9 (25.9) at 6 months postsurgery. Eighty participants (39.2%) had restricted mobility presurgery, 114 (56.4%) at 2 months postsurgery, and 84 (41.2%) at 6 months postsurgery. Restricted mobility was associated with being a woman (odds ratio [OR], 4.72; 95% CI, 2.27-9.84), greater frailty (OR, 10.42; 95% CI, 3.56-30.49), and concurrent need for support from formal or informal caregivers (OR, 5.43; 95% CI, 2.72-10.86). Elevated-risk surgery was associated with hospital readmission at 6 months (OR, 3.18; 95% CI, 1.48-7.25). Conclusions and Relevance: In this nested cohort study, mean LSM recovered by 6 months postsurgery, but 41% of older adults still had restricted mobility. Being a woman, having greater frailty, and needing support from caregivers were associated with poor recovery. Integrating life-space assessments into individualized perioperative care planning may enhance evaluation of functional recovery, inform shared decision-making, and guide support strategies.

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Journal
JAMA Network Open
Published
2026-07-22
DOI
https://doi.org/10.1001/jamanetworkopen.2026.24553
Primary Topic
Frailty in Older Adults
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article
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article

Life-Space Mobility Trajectories After Elective Surgery in Older Adults

Tyler R. Chesney, Nelly Toledano, N Siddiqui, Janet van Vlymen et al.
JAMA Network Open
Frailty in Older Adults
article

Life-Space Mobility Trajectories After Elective Surgery in Older Adults

Tyler R. Chesney, Nelly Toledano, N Siddiqui, Janet van Vlymen, Lisa Del Giudice, Kristen R. Haase, Eric Jacobsohn, Kerry Kuluski, Katherine S. McGilton, Matteo Parotto, Fay Bennie, Eric Pitters, Alexander J. Gregory, Puts Mt, Su-Yin MacDonell, Melinda Davis, Anne Stephens, S. McCluskey, Nicholas Legacy, Karim S. Ladha, Gianni R. Lorello, Emily Hladkowicz, Angela Jerath, Shabbir M. H. Alibhai, C. David Mazer, Keying Xu, Noah Crampton, Duminda N. Wijeysundera, Nai-Wen Ku, Daniel I. McIsaac
article en

Abstract

Importance: The number of older adults living with frailty who undergo surgery is rapidly increasing worldwide. Life-space mobility (LSM) can capture physical and social dimensions of recovery and has been linked to functional decline and reduced quality of life. Objective: To examine postoperative recovery using LSM among older adults living with frailty and to identify factors associated with restricted mobility and readmission. Design, Setting, and Participants: This cohort study within the larger Functional Improvement Trajectories After Surgery study used a convergent mixed-methods exploratory design. Seventeen hospitals across Canada included older adults aged 65 years or older with a clinical frailty score (CFS) of 3 or more who underwent major elective noncardiac surgery from March 2021 to June 2023. Data were analyzed from September to October 2025. Exposure: Elective noncardiac surgery among older adults. Main Outcomes and Measures: LSM (range 0-120, with higher scores indicating more mobility) was measured at 1 to 2 months and 6 months postoperatively, with retrospective presurgery LSM captured at 1 to 2 months. Multivariable linear mixed-effects models and multivariable mixed-effects logistic regression were used to identify factors associated with LSM trajectories, restricted mobility (ie, LSM < 60), and hospital readmission. Results: This study included 204 participants (mean [SD] age, 72.8 [5.6] years; 108 males [53%]). The mean (SD) LSM was 65.1 (26.7) presurgery, 56.6 (26.7) at 2 months postsurgery, and 64.9 (25.9) at 6 months postsurgery. Eighty participants (39.2%) had restricted mobility presurgery, 114 (56.4%) at 2 months postsurgery, and 84 (41.2%) at 6 months postsurgery. Restricted mobility was associated with being a woman (odds ratio [OR], 4.72; 95% CI, 2.27-9.84), greater frailty (OR, 10.42; 95% CI, 3.56-30.49), and concurrent need for support from formal or informal caregivers (OR, 5.43; 95% CI, 2.72-10.86). Elevated-risk surgery was associated with hospital readmission at 6 months (OR, 3.18; 95% CI, 1.48-7.25). Conclusions and Relevance: In this nested cohort study, mean LSM recovered by 6 months postsurgery, but 41% of older adults still had restricted mobility. Being a woman, having greater frailty, and needing support from caregivers were associated with poor recovery. Integrating life-space assessments into individualized perioperative care planning may enhance evaluation of functional recovery, inform shared decision-making, and guide support strategies.

JAMA Network OpenVol. 9(7)
St. Michael's Hospital (CA), Providence Health Care (CA), Sunnybrook Health Science Centre (CA), University Health Network (CA), University of British Columbia (CA), University of Calgary (CA), University of Toronto (CA), Toronto Western Hospital (CA), Toronto Rehabilitation Institute (CA), Trillium Health Centre (CA), Ottawa Hospital (CA), Women's College Hospital (CA), Health Sciences Centre (CA), Princess Margaret Cancer Centre (CA), St Michael’s Hospital (IE), Public Health Ontario (CA), Sinai Health System (CA), Centre for Global Health Research (CA), The Wilson Centre (CA), Kingston Health Sciences Centre (CA), Unity Health Toronto, University of Manitoba (CA), Libin Cardiovascular Institute of Alberta (CA)
Openalex Percentile: Top 11%
Frailty in Older Adults
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