Time Lost Is Brain Lost: Insights into Acute Ischaemic Stroke Delays in a Tertiary Care Super-speciality Centre in Jharkhand

Background Early hospital arrival is essential for timely thrombolysis in acute ischaemic stroke. However, many patients in low-resource settings continue to reach tertiary care centres beyond the recommended treatment window. Purpose To evaluate pre-hospital and in-hospital delays among patients with acute ischaemic stroke in Jharkhand and identify factors associated with timely hospital arrival. Methods A prospective observational study included 237 consecutive patients with acute ischaemic stroke admitted to a tertiary care hospital in Ranchi (July 2022–August 2024). Patients were classified as early (≤4.5 h) or delayed (>4.5 h), and multivariable logistic regression identified predictors of early hospital arrival. Results Only 15 patients (6.3%) reached the hospital within 4.5 h. Most were men, older adults and from rural, socio-economically disadvantaged backgrounds. Most (85.7%) first visited a nearby non-specialist healthcare facility, while awareness of stroke symptoms (14.0%) and thrombolysis (5.5%) was poor. Timely arrival was less likely after visiting a nearby healthcare facility (aOR 0.005, p < .001) but more likely with higher socio-economic status (aOR 17.02, p = .016) and ambulance availability (aOR 6.11, p = .021). Conclusion Improving ambulance services, referral pathways and public awareness may reduce delays and improve timely stroke treatment.

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Publication Details

Journal
Annals of Neurosciences
Published
2026-07-18
DOI
https://doi.org/10.1177/09727531261452861
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
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article

Time Lost Is Brain Lost: Insights into Acute Ischaemic Stroke Delays in a Tertiary Care Super-speciality Centre in Jharkhand

Surendra Kumar, Anupa Prasad, Vivek Verma, Lakhan Majhee et al.
Annals of Neurosciences
Acute Ischemic Stroke Management
article

Time Lost Is Brain Lost: Insights into Acute Ischaemic Stroke Delays in a Tertiary Care Super-speciality Centre in Jharkhand

Surendra Kumar, Anupa Prasad, Vivek Verma, Lakhan Majhee, Ganesh Chauhan, Amit Kumar, Yuvraj Sinha, Tannu Kumari
article en

Abstract

Background Early hospital arrival is essential for timely thrombolysis in acute ischaemic stroke. However, many patients in low-resource settings continue to reach tertiary care centres beyond the recommended treatment window. Purpose To evaluate pre-hospital and in-hospital delays among patients with acute ischaemic stroke in Jharkhand and identify factors associated with timely hospital arrival. Methods A prospective observational study included 237 consecutive patients with acute ischaemic stroke admitted to a tertiary care hospital in Ranchi (July 2022–August 2024). Patients were classified as early (≤4.5 h) or delayed (>4.5 h), and multivariable logistic regression identified predictors of early hospital arrival. Results Only 15 patients (6.3%) reached the hospital within 4.5 h. Most were men, older adults and from rural, socio-economically disadvantaged backgrounds. Most (85.7%) first visited a nearby non-specialist healthcare facility, while awareness of stroke symptoms (14.0%) and thrombolysis (5.5%) was poor. Timely arrival was less likely after visiting a nearby healthcare facility (aOR 0.005, p < .001) but more likely with higher socio-economic status (aOR 17.02, p = .016) and ambulance availability (aOR 6.11, p = .021). Conclusion Improving ambulance services, referral pathways and public awareness may reduce delays and improve timely stroke treatment.

Annals of Neurosciences
Rajendra Institute of Medical Sciences (IN), Assam University (IN)
No poverty
Openalex Percentile: Top 8%
Acute Ischemic Stroke Management
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