Machine unlearning as a governance imperative for clinical AI

Clinical AI assumes that the influence of training data can persist indefinitely. This premise fails when patients withdraw consent, evidence evolves, or bias is identified. Machine unlearning aims to remove specific data influence without full retraining. We argue that unlearning readiness should be built into the infrastructure of high-risk healthcare AI across patient autonomy, clinical validity, and system governance, and we outline a governance pathway to keep updates auditable and clinically safe.

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Publication Details

Journal
npj Digital Medicine
Published
2026-07-18
DOI
https://doi.org/10.1038/s41746-026-03050-1
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

Machine unlearning as a governance imperative for clinical AI

Simon Lucey, Hemanth Saratchandran, Arpit Garg, Johan Verjans et al.
npj Digital Medicine
Artificial Intelligence in Healthcare and Education
article

Machine unlearning as a governance imperative for clinical AI

Simon Lucey, Hemanth Saratchandran, Arpit Garg, Johan Verjans, Anthony Porter, Emily Kirkpatrick
article en

Abstract

Clinical AI assumes that the influence of training data can persist indefinitely. This premise fails when patients withdraw consent, evidence evolves, or bias is identified. Machine unlearning aims to remove specific data influence without full retraining. We argue that unlearning readiness should be built into the infrastructure of high-risk healthcare AI across patient autonomy, clinical validity, and system governance, and we outline a governance pathway to keep updates auditable and clinically safe.

npj Digital Medicine
South Australia Pathology (AU), SA Health (AU), Australian Centre for Robotic Vision (AU), South Australian Health and Medical Research Institute (AU), Central Adelaide Local Health Network, The University of Adelaide (AU)
Industry, innovation and infrastructure
Openalex Percentile: Top 11%
Artificial Intelligence in Healthcare and Education
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