Adult-Onset IgA Vasculitis Initially Attributed to a Cutaneous Drug Reaction and Diverticulitis

Immunoglobulin A vasculitis (IgAV), formerly Henoch–Schönlein purpura, is a small-vessel vasculitis characterized by palpable purpura, arthralgias, gastrointestinal involvement, and renal disease. Although IgAV is common in children, adult-onset disease is rare and may be associated with more severe manifestations, particularly renal involvement. In adults, IgAV may be difficult to recognize because of overlap with more common gastrointestinal, infectious, or medication-related conditions. We present a case of adult-onset IgAV initially attributed to presumed diverticulitis and later to a drug eruption following antibiotic exposure. This case highlights diagnostic pitfalls and the importance of early recognition and renal surveillance.

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Journal
Journal of Community Hospital Internal Medicine Perspectives
Published
2026-07-17
DOI
https://doi.org/10.55729/2000-9666.1626
Primary Topic
Vasculitis and related conditions
Type
article
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article

Adult-Onset IgA Vasculitis Initially Attributed to a Cutaneous Drug Reaction and Diverticulitis

Leila C Tou, Sarah Koraym, Shane Devine, Catherine Grace P. Hobayan
Journal of Community Hospital Internal Medicine Perspectives
Vasculitis and related conditions
article

Adult-Onset IgA Vasculitis Initially Attributed to a Cutaneous Drug Reaction and Diverticulitis

Leila C Tou, Sarah Koraym, Shane Devine, Catherine Grace P. Hobayan
article en

Abstract

Immunoglobulin A vasculitis (IgAV), formerly Henoch–Schönlein purpura, is a small-vessel vasculitis characterized by palpable purpura, arthralgias, gastrointestinal involvement, and renal disease. Although IgAV is common in children, adult-onset disease is rare and may be associated with more severe manifestations, particularly renal involvement. In adults, IgAV may be difficult to recognize because of overlap with more common gastrointestinal, infectious, or medication-related conditions. We present a case of adult-onset IgAV initially attributed to presumed diverticulitis and later to a drug eruption following antibiotic exposure. This case highlights diagnostic pitfalls and the importance of early recognition and renal surveillance.

Journal of Community Hospital Internal Medicine PerspectivesVol. 16(4)
Wright State University (US)
Good health and well-being
Openalex Percentile: Top 8%
Vasculitis and related conditions
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