Is tapering and stopping of tofacitinib possible among pediatric and adolescent alopecia areata patients?

Alopecia areata (AA) is an autoimmune condition characterized by non-scarring patchy alopecia.e condition affects all age groups, and an early age of onset (<12 years) is associated with an increased risk of developing chronic alopecia areata (CAA) and alopecia Totalis/universalis (AT/ AU), which may lead to a poor response to therapy. [1]Among all patients of AA, almost half experience disease onset within the first two decades of life, making it the most common cause of alopecia in children. [2]e various available treatment options for moderate to severe AA include topical immunotherapy/ contact irritants, systemic steroids, and steroid-sparing agents like cyclosporine, azathioprine, methotrexate, and the Janus kinase inhibitors.

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Publication Details

Journal
Cosmoderma
Published
2026-07-18
DOI
https://doi.org/10.25259/csdm_94_2026
Primary Topic
Hair Growth and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Is tapering and stopping of tofacitinib possible among pediatric and adolescent alopecia areata patients?

Richa Sharma, Archi Ranka, Rachita S Dhurat, Grishma Kale
Cosmoderma
Hair Growth and Disorders
article

Is tapering and stopping of tofacitinib possible among pediatric and adolescent alopecia areata patients?

Richa Sharma, Archi Ranka, Rachita S Dhurat, Grishma Kale
article en

Abstract

Alopecia areata (AA) is an autoimmune condition characterized by non-scarring patchy alopecia.e condition affects all age groups, and an early age of onset (<12 years) is associated with an increased risk of developing chronic alopecia areata (CAA) and alopecia Totalis/universalis (AT/ AU), which may lead to a poor response to therapy. [1]Among all patients of AA, almost half experience disease onset within the first two decades of life, making it the most common cause of alopecia in children. [2]e various available treatment options for moderate to severe AA include topical immunotherapy/ contact irritants, systemic steroids, and steroid-sparing agents like cyclosporine, azathioprine, methotrexate, and the Janus kinase inhibitors.

CosmodermaVol. 6
Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College (IN), Gujarat Cancer Society (IN), Mahatma Gandhi Mission Medical College and Hospital (IN)
No poverty
Openalex Percentile: Top 6%
Hair Growth and Disorders
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