Axillary cat-scratch disease: A case report and literature review

RATIONALE: Cat-scratch disease (CSD) typically presents as self-limited regional lymphadenopathy following a cat scratch or exposure. Its clinical features can mimic malignancy or tuberculosis, especially in elderly patients, leading to potential misdiagnosis. This report underscores the importance of considering CSD in elderly individuals with unexplained fever and atypical lymphadenopathy. PATIENT CONCERNS: A 67-year-old woman presented with a 3-month history of left axillary swelling, accompanied by pain and fever for 3 days. DIAGNOSES: Axillary CSD was confirmed based on clinical presentation, exposure history, and lymph node biopsy findings. INTERVENTIONS: The patient received compound sulfamethoxazole tablets as anti-infective therapy. OUTCOMES: Two weeks post-treatment, the patient was afebrile, and the surgical incision had healed. LESSONS: This case highlights the diagnostic challenges of CSD in the elderly. Early lymph node biopsy and careful elicitation of exposure history are essential to avoid misdiagnosis, particularly with malignancy. Timely intervention can prevent unnecessary procedures and improve prognosis. Evaluation of confirmed cases should also include an assessment for potential extra-nodal spread to sites such as the liver, colon, and retina.

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Journal
Medicine
Published
2026-07-17
DOI
https://doi.org/10.1097/md.0000000000049722
Primary Topic
Bartonella species infections research
Type
article
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article

Axillary cat-scratch disease: A case report and literature review

Mingshuang Li, C Chen
Medicine
Bartonella species infections research
article

Axillary cat-scratch disease: A case report and literature review

Mingshuang Li, C Chen
article en

Abstract

RATIONALE: Cat-scratch disease (CSD) typically presents as self-limited regional lymphadenopathy following a cat scratch or exposure. Its clinical features can mimic malignancy or tuberculosis, especially in elderly patients, leading to potential misdiagnosis. This report underscores the importance of considering CSD in elderly individuals with unexplained fever and atypical lymphadenopathy. PATIENT CONCERNS: A 67-year-old woman presented with a 3-month history of left axillary swelling, accompanied by pain and fever for 3 days. DIAGNOSES: Axillary CSD was confirmed based on clinical presentation, exposure history, and lymph node biopsy findings. INTERVENTIONS: The patient received compound sulfamethoxazole tablets as anti-infective therapy. OUTCOMES: Two weeks post-treatment, the patient was afebrile, and the surgical incision had healed. LESSONS: This case highlights the diagnostic challenges of CSD in the elderly. Early lymph node biopsy and careful elicitation of exposure history are essential to avoid misdiagnosis, particularly with malignancy. Timely intervention can prevent unnecessary procedures and improve prognosis. Evaluation of confirmed cases should also include an assessment for potential extra-nodal spread to sites such as the liver, colon, and retina.

MedicineVol. 105(29)
Wenzhou Medical University (CN), Zhejiang Taizhou Hospital (CN), Taizhou University (CN)
Good health and well-being
Openalex Percentile: Top 7%
Bartonella species infections research
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Axillary cat-scratch disease: A case report and literature review — Mingshuang Li, C Chen · Medicine (2026) | TGRS Research Map | TGRS