STEMI in a Patient With Aspirin‐Induced Angioedema: A Case for Early Desensitization

We report a 47-year-old male presenting with inferior ST-segment elevation myocardial infarction (STEMI) and a history of aspirin-induced angioedema. Despite the challenges of antithrombotic management in the context of aspirin allergy, the patient underwent successful primary percutaneous coronary intervention (PCI), followed by early in-hospital aspirin desensitization. This case highlights the feasibility and safety of early desensitization, allowing timely initiation of guideline-recommended dual antiplatelet therapy in a high risk setting.

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Publication Details

Journal
Catheterization and Cardiovascular Interventions
Published
2026-07-17
DOI
https://doi.org/10.1002/ccd.70751
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

STEMI in a Patient With Aspirin‐Induced Angioedema: A Case for Early Desensitization

Georges Namnoum, MAROUN SFEIR
Catheterization and Cardiovascular Interventions
Drug-Induced Adverse Reactions
article

STEMI in a Patient With Aspirin‐Induced Angioedema: A Case for Early Desensitization

Georges Namnoum, MAROUN SFEIR
article en

Abstract

We report a 47-year-old male presenting with inferior ST-segment elevation myocardial infarction (STEMI) and a history of aspirin-induced angioedema. Despite the challenges of antithrombotic management in the context of aspirin allergy, the patient underwent successful primary percutaneous coronary intervention (PCI), followed by early in-hospital aspirin desensitization. This case highlights the feasibility and safety of early desensitization, allowing timely initiation of guideline-recommended dual antiplatelet therapy in a high risk setting.

Catheterization and Cardiovascular Interventions
Institute Mutualiste Montsouris (FR)
Good health and well-being
Openalex Percentile: Top 9%
Drug-Induced Adverse Reactions
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