Epidemiology of Children and Young People Presenting to Australian Emergency Departments for the Management of Acute Severe Behavioural Disturbance: Secondary Analysis of a Randomised Controlled Trial

AIM: To describe the epidemiological characteristics of children and young people presenting to the emergency department (ED) with acute severe behavioural disturbance (ASBD) who were deemed to require oral sedative medication. METHODS: Secondary analysis of a randomised controlled open-label multi-centre trial of oral olanzapine versus oral diazepam for the management of ASBD in children and young people aged nine to 17 years for whom epidemiological data were recorded. RESULTS: There were 348 participants enrolled in the randomised controlled trial (RCT). The majority were female (215/348, 62%) with a mean age of 14.6 years (standard deviation 2.2). The most common pre-existing medical or mental health condition was anxiety (122/299, 35%) followed by attention deficit hyperactivity disorder and autism spectrum disorder (33% and 32%, respectively). Two-thirds of the study population (216/348, 62%) had previously attended the ED for ASBD management and 61% (212/348) reported previous intentional self-harm. Nearly three-quarters (247/348, 71%) were accessing psychiatric care in the community prior to their ED presentation. Half of the study population (178/348, 52%) presented to the ED with emergency services (e.g., ambulance, police). The median length of stay in the ED was 5.7 h (interquartile range 3.9-10.2 h) and 28% (98/348) of study participants required admission to hospital. CONCLUSIONS: For children and young people presenting to the ED with ASBD who were deemed to require oral sedative medication to assist with behavioural containment, pre-existing mental health disorders were common. There is a need for focussed management procedures for more targeted, trauma-focussed care for children and young people presenting to the ED with ASBD and for support and education in the pre-hospital setting. TRIAL REGISTRATION: The primary study (PEAChY-O) was registered with the Australian and New Zealand Clinical Trials Registry (ANZCTR) (ACTRN12621001236886) prior to commencement.

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Journal
Journal of Paediatrics and Child Health
Published
2026-07-17
DOI
https://doi.org/10.1111/jpc.70499
Primary Topic
Suicide and Self-Harm Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Epidemiology of Children and Young People Presenting to Australian Emergency Departments for the Management of Acute Severe Behavioural Disturbance: Secondary Analysis of a Randomised Controlled Trial

Meredith Louise Borland, Jonathan Knott, Chidambaram Prakash, Deborah Shellshear et al.
Journal of Paediatrics and Child Health
Suicide and Self-Harm Studies
article

Epidemiology of Children and Young People Presenting to Australian Emergency Departments for the Management of Acute Severe Behavioural Disturbance: Secondary Analysis of a Randomised Controlled Trial

Meredith Louise Borland, Jonathan Knott, Chidambaram Prakash, Deborah Shellshear, Catherine Wilson, Simon S. Craig, Amit Kochar, Andrew Davidson, Elyssia Bourke, Doris Tham, Shefali Jani, Chris J Selman, Katherine J. Lee, Gaby Nieva, NJ Phillips, Kate Klein, Michael Gordon, Franz E. Babl, Shane George
article en

Abstract

AIM: To describe the epidemiological characteristics of children and young people presenting to the emergency department (ED) with acute severe behavioural disturbance (ASBD) who were deemed to require oral sedative medication. METHODS: Secondary analysis of a randomised controlled open-label multi-centre trial of oral olanzapine versus oral diazepam for the management of ASBD in children and young people aged nine to 17 years for whom epidemiological data were recorded. RESULTS: There were 348 participants enrolled in the randomised controlled trial (RCT). The majority were female (215/348, 62%) with a mean age of 14.6 years (standard deviation 2.2). The most common pre-existing medical or mental health condition was anxiety (122/299, 35%) followed by attention deficit hyperactivity disorder and autism spectrum disorder (33% and 32%, respectively). Two-thirds of the study population (216/348, 62%) had previously attended the ED for ASBD management and 61% (212/348) reported previous intentional self-harm. Nearly three-quarters (247/348, 71%) were accessing psychiatric care in the community prior to their ED presentation. Half of the study population (178/348, 52%) presented to the ED with emergency services (e.g., ambulance, police). The median length of stay in the ED was 5.7 h (interquartile range 3.9-10.2 h) and 28% (98/348) of study participants required admission to hospital. CONCLUSIONS: For children and young people presenting to the ED with ASBD who were deemed to require oral sedative medication to assist with behavioural containment, pre-existing mental health disorders were common. There is a need for focussed management procedures for more targeted, trauma-focussed care for children and young people presenting to the ED with ASBD and for support and education in the pre-hospital setting. TRIAL REGISTRATION: The primary study (PEAChY-O) was registered with the Australian and New Zealand Clinical Trials Registry (ANZCTR) (ACTRN12621001236886) prior to commencement.

Journal of Paediatrics and Child Health
Griffith University (AU), The Royal Melbourne Hospital (AU), Royal Children's Hospital (AU), The University of Queensland (AU), The University of Melbourne (AU), The University of Western Australia (AU), Gold Coast Hospital (AU), Princess Margaret Hospital for Children (AU), Women's and Children's Hospital (AU), Monash Medical Centre (AU), Children's Hospital at Westmead (AU), Sunshine Hospital (AU), Murdoch Children's Research Institute (AU), Children's Health Queensland Hospital and Health Service (AU), Perth Children's Hospital, Monash University (AU), The University of Adelaide (AU)
National Health and Medical Research Council
Good health and well-being
Openalex Percentile: Top 6%
Suicide and Self-Harm Studies
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