Basal Ganglia Lesion Associated With Faciobrachial Dystonic Seizures (FBDS) in Anti‐LGI1 Encephalitis: A Clinicopathological Case Report

This case provides clinicopathological evidence supporting the association between FBDS and basal ganglia involvement in anti-LGI1 encephalitis. It highlights the diagnostic challenge posed by tumour-like unilateral basal ganglia lesions on MRI and underscores the importance of neuronal autoantibody testing before invasive procedures. In addition, this report contributes the first neuropathological description of basal ganglia involvement in anti-LGI1 encephalitis and summarises previously reported pathological findings.

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Publication Details

Journal
Neuropathology and Applied Neurobiology
Published
2026-07-17
DOI
https://doi.org/10.1111/nan.70094
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Basal Ganglia Lesion Associated With Faciobrachial Dystonic Seizures (FBDS) in Anti‐LGI1 Encephalitis: A Clinicopathological Case Report

Pinfei Ni, Siyuan Fan, Hongzhi Guan, Haitao Ren
Neuropathology and Applied Neurobiology
Autoimmune Neurological Disorders and Treatments
article

Basal Ganglia Lesion Associated With Faciobrachial Dystonic Seizures (FBDS) in Anti‐LGI1 Encephalitis: A Clinicopathological Case Report

Pinfei Ni, Siyuan Fan, Hongzhi Guan, Haitao Ren
article en

Abstract

This case provides clinicopathological evidence supporting the association between FBDS and basal ganglia involvement in anti-LGI1 encephalitis. It highlights the diagnostic challenge posed by tumour-like unilateral basal ganglia lesions on MRI and underscores the importance of neuronal autoantibody testing before invasive procedures. In addition, this report contributes the first neuropathological description of basal ganglia involvement in anti-LGI1 encephalitis and summarises previously reported pathological findings.

Neuropathology and Applied NeurobiologyVol. 52(4)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Good health and well-being
Openalex Percentile: Top 8%
Autoimmune Neurological Disorders and Treatments
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