Encapsulation of Bioactive Compounds Using Colloidal Delivery Systems: Challenges and Potential for Commercial Nutraceutical Formulations

The increasing demand for nutraceutical products formulated from bioactive compounds has prompted the development and application of encapsulation technologies to facilitate their incorporation and enhance their efficacy. Bioactive compounds derived from various sources, including plants, animals, and microorganisms, are integral to the formulation of nutraceuticals with health-promoting properties. However, challenges such as poor dispersibility, chemical stability, bioaccessibility, and bioavailability currently hinder the development of effective commercial products. Encapsulation technologies can be employed to overcome these obstacles, thereby paving the way for greater innovation and success in the nutraceutical industry. However, to meet the growing demands for commercial functional food and personalized nutrition products, it will be imperative to address product optimization, scale-up, economic challenges, and safety concerns, as well as to ensure regulatory compliance, meet consumer perceptions, and address environmental and sustainability concerns. This review discusses the current status of the development and application of nutraceutical products, with a strong emphasis on the potential and challenges associated with their commercial success.

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Publication Details

Journal
ACS Applied Engineering Materials
Published
2026-07-17
DOI
https://doi.org/10.1021/acsaenm.6c00553
Primary Topic
Microencapsulation and Drying Processes
Type
article
Field-Weighted Citation Impact
0.00

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article

Encapsulation of Bioactive Compounds Using Colloidal Delivery Systems: Challenges and Potential for Commercial Nutraceutical Formulations

Sarawut Cheunkar, Sukunya Oaew, Wei Liu, Asmita Khanal
ACS Applied Engineering Materials
Microencapsulation and Drying Processes
article

Encapsulation of Bioactive Compounds Using Colloidal Delivery Systems: Challenges and Potential for Commercial Nutraceutical Formulations

Sarawut Cheunkar, Sukunya Oaew, Wei Liu, Asmita Khanal
article en

Abstract

The increasing demand for nutraceutical products formulated from bioactive compounds has prompted the development and application of encapsulation technologies to facilitate their incorporation and enhance their efficacy. Bioactive compounds derived from various sources, including plants, animals, and microorganisms, are integral to the formulation of nutraceuticals with health-promoting properties. However, challenges such as poor dispersibility, chemical stability, bioaccessibility, and bioavailability currently hinder the development of effective commercial products. Encapsulation technologies can be employed to overcome these obstacles, thereby paving the way for greater innovation and success in the nutraceutical industry. However, to meet the growing demands for commercial functional food and personalized nutrition products, it will be imperative to address product optimization, scale-up, economic challenges, and safety concerns, as well as to ensure regulatory compliance, meet consumer perceptions, and address environmental and sustainability concerns. This review discusses the current status of the development and application of nutraceutical products, with a strong emphasis on the potential and challenges associated with their commercial success.

ACS Applied Engineering Materials
Institute of Biosciences and Bioresources (IT), Research Institute "Pilot" (Russia) (RU), King Mongkut's University of Technology Thonburi (TH), National Center for Genetic Engineering and Biotechnology (TH)
King Mongkut's University of Technology Thonburi
Zero hunger
Openalex Percentile: Top 11%
Microencapsulation and Drying Processes
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Encapsulation of Bioactive Compounds Using Colloidal Delivery Systems: Challenges and Potential for Commercial Nutraceutical Formulations — Sarawut Cheunkar, Sukunya Oaew, et al. · ACS Applied Engineering Materials (2026) | TGRS Research Map | TGRS