IRAK-M attenuates pain hypersensitivity and anxiety-like behaviors in a nitroglycerin-induced chronic migraine mouse model with concomitant reductions in microglial activation and neuroinflammation

Authors

Yun-Yan Zhao
Wei Xie (ORCID: https://orcid.org/0000-0002-3218-7231)
Yifan Xiong (ORCID: https://orcid.org/0000-0002-1168-9179)
Xiao-Shan Liang
Xi-mao Liu
Xiaotao Liang
Ding Yue-Wen
Xi Zhu (ORCID: https://orcid.org/0000-0003-1342-2221)
Z Z Wu
Yu Hong
Yu-Heng Zou
Shi-Ru Xie

Institutions

Guangzhou University of Chinese Medicine (CN)
Beth Israel Deaconess Medical Center (US)
Nanfang Hospital (CN)
Southern Medical University (CN)
Guangzhou Medical University (CN)

Publication Details

Journal: The Journal of Headache and Pain
Published: 2026-07-17
DOI: https://doi.org/10.1186/s10194-026-02457-1
Primary Topic: Migraine and Headache Studies
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Natural Science Foundation of China
China Postdoctoral Science Foundation
Basic and Applied Basic Research Foundation of Guangdong Province

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article

IRAK-M attenuates pain hypersensitivity and anxiety-like behaviors in a nitroglycerin-induced chronic migraine mouse model with concomitant reductions in microglial activation and neuroinflammation

Yun-Yan Zhao, Wei Xie, Yifan Xiong, Xiao-Shan Liang et al.

Jul 17, 2026

The Journal of Headache and Pain

Migraine and Headache Studies

article

IRAK-M attenuates pain hypersensitivity and anxiety-like behaviors in a nitroglycerin-induced chronic migraine mouse model with concomitant reductions in microglial activation and neuroinflammation

Yun-Yan Zhao, Wei Xie, Yifan Xiong, Xiao-Shan Liang, Xi-mao Liu, Xiaotao Liang, Ding Yue-Wen, Xi Zhu, Z Z Wu, Yu Hong, Yu-Heng Zou, Shi-Ru Xie

July 17, 2026article en

Abstract

No abstract available for this paper.

The Journal of Headache and Pain

Guangzhou University of Chinese Medicine (CN), Beth Israel Deaconess Medical Center (US), Nanfang Hospital (CN), Southern Medical University (CN), Guangzhou Medical University (CN)

National Natural Science Foundation of China, China Postdoctoral Science Foundation, Basic and Applied Basic Research Foundation of Guangdong Province

Good health and well-being

Openalex Percentile: Top 8%

Migraine and Headache Studies

DOI Open Access PDF OpenAlex

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IRAK-M attenuates pain hypersensitivity and anxiety-like behaviors in a nitroglycerin-induced chronic migraine mouse model with concomitant reductions in microglial activation and neuroinflammation — Yun-Yan Zhao, Wei Xie, et al. · The Journal of Headache and Pain (2026) | TGRS Research Map | TGRS