High-gain and broadband in vivo amplifiers enabled by matched materials

, a bandwidth above 600 Hz at 0.6 V, and an ultralow power consumption down to 0.57 nW at 0.2 V. We further demonstrate in vivo amplification of mouse electrocorticographic (ECoG) signal with good biocompatibility and superior signal quality. This work establishes a general material-device-circuit framework and design guidelines for OECT-based amplifiers.

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Publication Details

Journal
Nature Communications
Published
2026-07-16
DOI
https://doi.org/10.1038/s41467-026-75627-z
Primary Topic
Photorefractive and Nonlinear Optics
Type
article
Field-Weighted Citation Impact
0.00

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article

High-gain and broadband in vivo amplifiers enabled by matched materials

Jingcao Xu, Jupeng Chen, Ting Lei, Jiatong Li et al.
Nature Communications
Photorefractive and Nonlinear Optics
article

High-gain and broadband in vivo amplifiers enabled by matched materials

Jingcao Xu, Jupeng Chen, Ting Lei, Jiatong Li, Xiaochuan Dai, Zhiyuan Xiong, Xiran Pan, Gaoyang Ge, Peiyun Li, Zhibo Ren, Xun Lei, Zhi Zhang, Wenxi Sun, Y J Zheng, Suqing Gao, Chengwen Wu, Yiheng Chen, Qi Li, Xinyue Wang, Wenlong Li, Biqin Yang, Siqi Fang
article en

Abstract

, a bandwidth above 600 Hz at 0.6 V, and an ultralow power consumption down to 0.57 nW at 0.2 V. We further demonstrate in vivo amplification of mouse electrocorticographic (ECoG) signal with good biocompatibility and superior signal quality. This work establishes a general material-device-circuit framework and design guidelines for OECT-based amplifiers.

Nature Communications
Ministry of Education (RO), Technische Universität Dresden (DE), Tsinghua University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Beijing Municipality, Beijing Nova Program, National Key Research and Development Program of China
Affordable and clean energy
Openalex Percentile: Top 10%
Photorefractive and Nonlinear Optics
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