Clinical Features and Outcomes in Patients with Acute Retinal Necrosis in Both Eyes at the Time of Initial Presentation – Bilateral Acute Retinal Necrosis (BARN)

PURPOSE: To analyze the clinical features and outcomes in patients presenting with Bilateral Acute Retinal Necrosis (BARN) at the time of initial presentation. METHODS: Retrospective, observational study of patients with bilateral Acute Retinal Necrosis (BARN) at a tertiary care center in South India from 2016 to 2025. Data collected included demographics, systemic and ocular history, BCVA (converted to logMAR for analysis), treatment modalities (medical and surgical), and complications such as retinal detachment, glaucoma, and phthisis bulbi. RESULTS: BARN was noted in 41 patients out of a total of 319 clinical records of ARN (12.8%). One-third patients (36.5%) had a history of HIV. The mean BCVA improved from 1.37 logMAR at presentation to 1.18 logMAR after a mean follow-up of 38.4 months. Rhegmatogenous retinal detachment (RRD) was the most common complication, affecting 36.5% (30/82) of eyes, with 8 eyes presenting with RRD and 22 developing it during follow-up. Exudative retinal detachment was noted in 7 eyes. Other complications included optic atrophy (10.9%), phthisis bulbi (4.8%), glaucoma (2.4%), and epiretinal membrane (1.2%). Medical treatment included antivirals and systemic corticosteroids. CONCLUSION: Bilateral acute retinal necrosis is uncommon but has more severe course and results in significant ocular complications and poor visual outcomes underscoring the aggressive nature of the disease.

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Journal
Ocular Immunology and Inflammation
Published
2026-07-16
DOI
https://doi.org/10.1080/09273948.2026.2689370
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
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article

Clinical Features and Outcomes in Patients with Acute Retinal Necrosis in Both Eyes at the Time of Initial Presentation – Bilateral Acute Retinal Necrosis (BARN)

Prapti Praful Chheda, Shaswat Behera, Samreen Mehfooz, ShravyaChoudhary Balla et al.
Ocular Immunology and Inflammation
Ocular Diseases and Behçet’s Syndrome
article

Clinical Features and Outcomes in Patients with Acute Retinal Necrosis in Both Eyes at the Time of Initial Presentation – Bilateral Acute Retinal Necrosis (BARN)

Prapti Praful Chheda, Shaswat Behera, Samreen Mehfooz, ShravyaChoudhary Balla, Rajeev Reddy Pappuru, Soumyava Basu, Mudit Tyagi, Shabtab Nasir
article en

Abstract

PURPOSE: To analyze the clinical features and outcomes in patients presenting with Bilateral Acute Retinal Necrosis (BARN) at the time of initial presentation. METHODS: Retrospective, observational study of patients with bilateral Acute Retinal Necrosis (BARN) at a tertiary care center in South India from 2016 to 2025. Data collected included demographics, systemic and ocular history, BCVA (converted to logMAR for analysis), treatment modalities (medical and surgical), and complications such as retinal detachment, glaucoma, and phthisis bulbi. RESULTS: BARN was noted in 41 patients out of a total of 319 clinical records of ARN (12.8%). One-third patients (36.5%) had a history of HIV. The mean BCVA improved from 1.37 logMAR at presentation to 1.18 logMAR after a mean follow-up of 38.4 months. Rhegmatogenous retinal detachment (RRD) was the most common complication, affecting 36.5% (30/82) of eyes, with 8 eyes presenting with RRD and 22 developing it during follow-up. Exudative retinal detachment was noted in 7 eyes. Other complications included optic atrophy (10.9%), phthisis bulbi (4.8%), glaucoma (2.4%), and epiretinal membrane (1.2%). Medical treatment included antivirals and systemic corticosteroids. CONCLUSION: Bilateral acute retinal necrosis is uncommon but has more severe course and results in significant ocular complications and poor visual outcomes underscoring the aggressive nature of the disease.

Ocular Immunology and Inflammation
L V Prasad Eye Institute (IN)
No poverty
Openalex Percentile: Top 6%
Ocular Diseases and Behçet’s Syndrome
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Clinical Features and Outcomes in Patients with Acute Retinal Necrosis in Both Eyes at the Time of Initial Presentation – Bilateral Acute Retinal Necrosis (BARN) — Prapti Praful Chheda, Shaswat Behera, et al. · Ocular Immunology and Inflammation (2026) | TGRS Research Map | TGRS