Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

ABSTRACT Objectives This prospective study aimed to assess the outcomes of laparoscopic sphincter‐preserving surgery in elderly patients with rectal cancer. Methods This study included patients over 65 years old with rectal cancer who underwent laparoscopic sphincter‐preserving surgery between 2015 and 2018. Patients with prior malignancies or abdominal surgeries were excluded. All patient data were collected, and the follow‐up was conducted over 5 years. Results A total of 78 patients underwent surgery with a median follow‐up of 65 months. The overall survival was approximately 80% at 3 years and 70% at 5 years. Notably, nearly half of the total deaths (11 out of 24) resulted from non‐cancer causes, including COVID‐19 and other comorbidities. Advanced T‐stage and tumor invasion were identified as the primary factors significantly associated with increased recurrence and mortality in univariate analyses. However, these factors did not remain statistically significant in multivariate models, likely due to the limited sample size of this geriatric cohort. Conclusion Laparoscopic sphincter‐preserving surgery is feasible for elderly patients, achieving a 70% 5‐year survival rate. However, the high recurrence risk in advanced T‐stage and invasive cases underscores the need for personalized geriatric protocols and more aggressive preoperative strategies for high‐risk subgroups.

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Publication Details

Journal
Aging and Cancer
Published
2026-07-16
DOI
https://doi.org/10.1002/aac2.70026
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
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article

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Huu Duc Ho, Van Viet Ung, Loc Vu, Quang Le et al.
Aging and Cancer
Colorectal Cancer Surgical Treatments
article

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Huu Duc Ho, Van Viet Ung, Loc Vu, Quang Le, Ngoc Thach Tran
article en

Abstract

ABSTRACT Objectives This prospective study aimed to assess the outcomes of laparoscopic sphincter‐preserving surgery in elderly patients with rectal cancer. Methods This study included patients over 65 years old with rectal cancer who underwent laparoscopic sphincter‐preserving surgery between 2015 and 2018. Patients with prior malignancies or abdominal surgeries were excluded. All patient data were collected, and the follow‐up was conducted over 5 years. Results A total of 78 patients underwent surgery with a median follow‐up of 65 months. The overall survival was approximately 80% at 3 years and 70% at 5 years. Notably, nearly half of the total deaths (11 out of 24) resulted from non‐cancer causes, including COVID‐19 and other comorbidities. Advanced T‐stage and tumor invasion were identified as the primary factors significantly associated with increased recurrence and mortality in univariate analyses. However, these factors did not remain statistically significant in multivariate models, likely due to the limited sample size of this geriatric cohort. Conclusion Laparoscopic sphincter‐preserving surgery is feasible for elderly patients, achieving a 70% 5‐year survival rate. However, the high recurrence risk in advanced T‐stage and invasive cases underscores the need for personalized geriatric protocols and more aggressive preoperative strategies for high‐risk subgroups.

Aging and Cancer
Vietnam National University Ho Chi Minh City (VN), University of Medicine and Pharmacy at Ho Chi Minh City (VN), Trường ĐH Nguyễn Tất Thành (VN), Methodist Hospital (US), HCMC Hospital of Dermato Venereology (VN), Tân Tạo University (VN), Pham Ngoc Thach Hospital (VN)
Good health and well-being
Openalex Percentile: Top 11%
Colorectal Cancer Surgical Treatments
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