Early parenteral prostacyclin therapy enables near-normal haemodynamics and treatment de-escalation in patients with haemodynamically severe pulmonary arterial hypertension

<title>Extract</title> About 20% of patients with haemodynamically severe PAH achieved near-normal haemodynamics and safely de-escalated parenteral prostacyclin. Early intensive treatment may be key to maintaining near-normal haemodynamics after prostacyclin discontinuation.

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Publication Details

Journal
European Respiratory Journal
Published
2026-07-16
DOI
https://doi.org/10.1183/13993003.00855-2026
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

Early parenteral prostacyclin therapy enables near-normal haemodynamics and treatment de-escalation in patients with haemodynamically severe pulmonary arterial hypertension

Takeshi Suetomi, Hiromi Matsubara, Syed Rehan Quadery, Hiroto Shimokawahara et al.
European Respiratory Journal
Pulmonary Hypertension Research and Treatments
article

Early parenteral prostacyclin therapy enables near-normal haemodynamics and treatment de-escalation in patients with haemodynamically severe pulmonary arterial hypertension

Takeshi Suetomi, Hiromi Matsubara, Syed Rehan Quadery, Hiroto Shimokawahara, Chiaki Goten, Keiichiro Kuronuma
article en

Abstract

<title>Extract</title> About 20% of patients with haemodynamically severe PAH achieved near-normal haemodynamics and safely de-escalated parenteral prostacyclin. Early intensive treatment may be key to maintaining near-normal haemodynamics after prostacyclin discontinuation.

European Respiratory Journal
Kanazawa University (JP), Yamaguchi University (JP), Okayama Medical Center (JP)
Good health and well-being
Openalex Percentile: Top 9%
Pulmonary Hypertension Research and Treatments
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