Prognostic impact of age and MDS-associated mutations in NPM1-mutated AML.
AML is not independently associated with adverse risk after adjusting for age, and highlight the need for age-adjusted AML risk models.
Authors
- Rhonda E. Ries (ORCID: https://orcid.org/0000-0002-3702-7923)
- Anna B. Moseley (ORCID: https://orcid.org/0000-0002-7514-7360)
- Min Fang (ORCID: https://orcid.org/0000-0003-0431-881X)
- Megan K. D. Othus (ORCID: https://orcid.org/0000-0001-8176-6371)
- Suravi Raychaudhuri (ORCID: https://orcid.org/0000-0001-6516-5293)
- Guangrong Qin (ORCID: https://orcid.org/0000-0001-8836-1246)
- Thomas R. Chauncey (ORCID: https://orcid.org/0000-0003-2815-7301)
- Soheil Meshinchi (ORCID: https://orcid.org/0000-0002-6276-4423)
- Harry Paul Erba (ORCID: https://orcid.org/0000-0003-1093-2189)
- Eliana Dietrich (ORCID: https://orcid.org/0009-0000-8836-0374)
- John E. Godwin (ORCID: https://orcid.org/0000-0003-3876-2505)
- Jasmine Naru (ORCID: https://orcid.org/0000-0003-3957-4039)
- Frederick R. Appelbaum (ORCID: https://orcid.org/0000-0002-1839-5069)
- Derek L. Stirewalt (ORCID: https://orcid.org/0000-0003-4151-3171)
- Cheryl L. Willman (ORCID: https://orcid.org/0000-0002-1524-2622)
- Stanley Chun-Wei Lee (ORCID: https://orcid.org/0000-0001-7110-2416)
- Vivian M. Liu (ORCID: https://orcid.org/0000-0002-9118-6204)
- Mary‐Elizabeth M. Percival (ORCID: https://orcid.org/0000-0002-7016-951X)
- Era L. Pogosova‐Agadjanyan (ORCID: https://orcid.org/0000-0002-9060-358X)
- Jerald P. Radich (ORCID: https://orcid.org/0000-0002-1618-230X)
- Matthew Fitzgibbon (ORCID: https://orcid.org/0009-0008-7557-0442)
Institutions
- Mayo Clinic (US)
- Duke University (US)
- University of Washington (US)
- Institute for Systems Biology (US)
- Fred Hutch Cancer Center (US)
- VA Puget Sound Health Care System (US)
- Duke Cancer Institute (US)
Publication Details
- Journal
- PubMed Central
- Published
- 2026-11-01
- DOI
- https://doi.org/10.1016/j.bneo.2026.100272
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fred Hutchinson Cancer Research Center
- University of Washington
- Hope Foundation
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- National Cancer Institute