Structure-property correlation study on biocompatibility of wire arc additively manufactured nitinol alloy

Wire arc additive manufacturing (WAAM) provides a cost-effective approach for fabricating NiTi alloys for biomedical applications. In this study, a NiTi alloy wall was fabricated using WAAM and systematically evaluated for its microstructure, mechanical properties, corrosion resistance, and biocompatibility. EBSD analysis showed mainly high-angle grain boundaries, while XRD confirmed the dominant B2 austenitic phase with minor B19′ martensite. Microhardness increased from 282 to 380 HV with increasing build height, while tensile strength ranged from 550 to 615 MPa. XPS analysis revealed a TiO 2 -rich passive surface layer, which enhanced wettability, as indicated by contact angles of 29.93° and 25.95°. Electrochemical testing measured a corrosion rate of 0.013 mm year −1 . Hemolysis was below 1%, and MG-63 cell viability reached 91.18%. These results show that WAAM-fabricated NiTi exhibits favorable structural integrity and biocompatibility, making it suitable for potential orthopedic implant applications.

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Journal
iScience
Published
2026-07-17
DOI
https://doi.org/10.1016/j.isci.2026.116678
Primary Topic
Additive Manufacturing Materials and Processes
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article
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article

Structure-property correlation study on biocompatibility of wire arc additively manufactured nitinol alloy

M. Vignesh, Sahil Gaba, Kaviya M
iScience
Additive Manufacturing Materials and Processes
article

Structure-property correlation study on biocompatibility of wire arc additively manufactured nitinol alloy

M. Vignesh, Sahil Gaba, Kaviya M
article en

Abstract

Wire arc additive manufacturing (WAAM) provides a cost-effective approach for fabricating NiTi alloys for biomedical applications. In this study, a NiTi alloy wall was fabricated using WAAM and systematically evaluated for its microstructure, mechanical properties, corrosion resistance, and biocompatibility. EBSD analysis showed mainly high-angle grain boundaries, while XRD confirmed the dominant B2 austenitic phase with minor B19′ martensite. Microhardness increased from 282 to 380 HV with increasing build height, while tensile strength ranged from 550 to 615 MPa. XPS analysis revealed a TiO 2 -rich passive surface layer, which enhanced wettability, as indicated by contact angles of 29.93° and 25.95°. Electrochemical testing measured a corrosion rate of 0.013 mm year −1 . Hemolysis was below 1%, and MG-63 cell viability reached 91.18%. These results show that WAAM-fabricated NiTi exhibits favorable structural integrity and biocompatibility, making it suitable for potential orthopedic implant applications.

iScienceVol. 29(8)
Regional Centre for Biotechnology (IN), Amrita Vishwa Vidyapeetham (IN)
Openalex Percentile: Top 16%
Additive Manufacturing Materials and Processes
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Structure-property correlation study on biocompatibility of wire arc additively manufactured nitinol alloy — M. Vignesh, Sahil Gaba, et al. · iScience (2026) | TGRS Research Map | TGRS