146P Dynamic folate receptor-α (FRα) expression in recurrent ovarian cancer patients undergoing secondary debulking surgery: A real-world analysis
FRα is a clinically actionable target in ovarian cancer, with mirvetuximab soravtansine approved in patients with high expression based on PS2 scoring. However, FRα expression may be heterogeneous and dynamic. Real-world data on FRα expression patterns and their clinical implications remain limited We evaluated temporal changes in FRα expression between primary and secondary debulking surgery (SDS).
Authors
- A-M. Papanota
- D. Haidopoulos
- M.A.C. Dimopoulos
- A. Michas
- N. Thomakos
- M. Liontos
- T. Papadopoulou
- M. Kaparelou
- A. Svarna
- D. Papatheodorou
- N.G. Dedes
- A. Andrikopoulou
Institutions
- National and Kapodistrian University of Athens (GR)
Publication Details
- Journal
- ESMO Open
- Published
- 2026-07-01
- DOI
- https://doi.org/10.1016/j.esmoop.2026.108193
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00