138P Results of the NOGGO PERCEPTION: Phase II investigational study of pembrolizumab in combination with chemotherapy in platinum-sensitive recurrent low-grade serous ovarian cancer

Low-grade serous ovarian cancer (LGSOC) is a rare malignancy with limited responsiveness to chemotherapy, highlighting the urgent need for novel therapeutic strategies to improve treatment outcomes. Immune checkpoint inhibitors, such as pembrolizumab, have demonstrated efficacy in various cancers, including certain ovarian cancer subtypes, and could represent a promising treatment option for LGSOC.

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Publication Details

Journal
ESMO Open
Published
2026-07-01
DOI
https://doi.org/10.1016/j.esmoop.2026.108185
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

138P Results of the NOGGO PERCEPTION: Phase II investigational study of pembrolizumab in combination with chemotherapy in platinum-sensitive recurrent low-grade serous ovarian cancer

D. Zocholl, F. Heitz, J. Sehouli, J. Welz et al.
ESMO Open
Ovarian cancer diagnosis and treatment
article

138P Results of the NOGGO PERCEPTION: Phase II investigational study of pembrolizumab in combination with chemotherapy in platinum-sensitive recurrent low-grade serous ovarian cancer

D. Zocholl, F. Heitz, J. Sehouli, J. Welz, E.I. Braicu, J.P. Grabowski, P. Harter, F. Schmeling, T. Arndt
article en

Abstract

Low-grade serous ovarian cancer (LGSOC) is a rare malignancy with limited responsiveness to chemotherapy, highlighting the urgent need for novel therapeutic strategies to improve treatment outcomes. Immune checkpoint inhibitors, such as pembrolizumab, have demonstrated efficacy in various cancers, including certain ovarian cancer subtypes, and could represent a promising treatment option for LGSOC.

ESMO OpenVol. 11
Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Kliniken Essen-Mitte (DE), Nord-Ostdeutsche Gesellschaft für Gynäkologische Onkologie (DE), Charité - Universitätsmedizin Berlin (DE)
Good health and well-being
Openalex Percentile: Top 6%
Ovarian cancer diagnosis and treatment
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138P Results of the NOGGO PERCEPTION: Phase II investigational study of pembrolizumab in combination with chemotherapy in platinum-sensitive recurrent low-grade serous ovarian cancer — D. Zocholl, F. Heitz, et al. · ESMO Open (2026) | TGRS Research Map | TGRS