142P Early-phase clinical trials in gynaecologic malignancies: A 13-year single-center experience

Patients (pts) with advanced gynaecologic cancers often progress after standard therapies. Phase I trials provide access to innovative agents and may offer clinical benefit in heavily pretreated populations. We retrospectively evaluated outcomes of pts enrolled in phase I trials at a single academic center over 13 years.

Authors

M. Imbimbo
C. Sessa
M. NERONE
I. Colombo
M. Iannace
L. Tortola
A. Stathis
C. Cafaro Greco
M. Pedrani
V. Ricco
A. Fossati
E. Bisdomini
A.P.A. Badellino
A. Gagliano
L. Pallavicini
H-M. Lin
A.R. Carvalho Mendonca
E.A. Ciliberti
N. Scahett
D. Coppola

Institutions

Institute of Oncology Research (CH)

Publication Details

Journal: ESMO Open
Published: 2026-07-01
DOI: https://doi.org/10.1016/j.esmoop.2026.108189
Primary Topic: Ovarian cancer diagnosis and treatment
Type: article
Field-Weighted Citation Impact: 0.00

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article

142P Early-phase clinical trials in gynaecologic malignancies: A 13-year single-center experience

M. Imbimbo, C. Sessa, M. NERONE, I. Colombo et al.

Jul 1, 2026

ESMO Open

Ovarian cancer diagnosis and treatment

article

142P Early-phase clinical trials in gynaecologic malignancies: A 13-year single-center experience

M. Imbimbo, C. Sessa, M. NERONE, I. Colombo, M. Iannace, L. Tortola, A. Stathis, C. Cafaro Greco, M. Pedrani, V. Ricco, A. Fossati, E. Bisdomini, A.P.A. Badellino, A. Gagliano, L. Pallavicini, H-M. Lin, A.R. Carvalho Mendonca, E.A. Ciliberti, N. Scahett, D. Coppola

July 1, 2026article en

Abstract

Patients (pts) with advanced gynaecologic cancers often progress after standard therapies. Phase I trials provide access to innovative agents and may offer clinical benefit in heavily pretreated populations. We retrospectively evaluated outcomes of pts enrolled in phase I trials at a single academic center over 13 years.

ESMO OpenVol. 11

Institute of Oncology Research (CH)

Openalex Percentile: Top 6%

Ovarian cancer diagnosis and treatment

DOI Open Access PDF OpenAlex

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