98eP Prognostic significance of p53 mutation in stage I endometrial cancer: A multi-centre cohort study

In Australia women have a 2.3% risk of endometrial cancer (EC). p53 mutation (p53m), often associated with poorer prognosis, guides adjuvant therapy following TCGA and FIGO 2023 updates. This study evaluated uptake of molecular testing and survival outcomes in stage 1 EC based on p53 status.

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Publication Details

Journal
ESMO Open
Published
2026-07-01
DOI
https://doi.org/10.1016/j.esmoop.2026.108124
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

98eP Prognostic significance of p53 mutation in stage I endometrial cancer: A multi-centre cohort study

P-S Kok, KM Wan, N. Huang, K. Wilkinson et al.
ESMO Open
Endometrial and Cervical Cancer Treatments
article

98eP Prognostic significance of p53 mutation in stage I endometrial cancer: A multi-centre cohort study

P-S Kok, KM Wan, N. Huang, K. Wilkinson, G. Shivasabesan, D. Pathiraja, G. Tang, A. Scott, M. Burling, C. Yau, S.L. Wong
article en

Abstract

In Australia women have a 2.3% risk of endometrial cancer (EC). p53 mutation (p53m), often associated with poorer prognosis, guides adjuvant therapy following TCGA and FIGO 2023 updates. This study evaluated uptake of molecular testing and survival outcomes in stage 1 EC based on p53 status.

ESMO OpenVol. 11
Camden and Campbelltown Hospitals (AU), Royal Hospital for Women (AU), Liverpool Hospital (AU), Monash Medical Centre (AU), Prince of Wales Hospital (AU), St George Hospital (AU), South Western Sydney Local Health District (AU)
No poverty
Openalex Percentile: Top 6%
Endometrial and Cervical Cancer Treatments
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