86P Payload-driven fatal toxicity signals of antibody–drug conjugates in endometrial cancer: A FAERS disproportionality analysis

Antibody–drug conjugates (ADCs) have expanded therapeutic options in gynecologic malignancies, including endometrial cancer, but are associated with potentially serious and fatal toxicities. This study evaluates the association between ADCs and adverse event profiles, including fatal outcomes, using the FDA Adverse Event Reporting System.

Authors

Institutions

Publication Details

Journal
ESMO Open
Published
2026-07-01
DOI
https://doi.org/10.1016/j.esmoop.2026.108112
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

86P Payload-driven fatal toxicity signals of antibody–drug conjugates in endometrial cancer: A FAERS disproportionality analysis

E.H. Hasanin
ESMO Open
HER2/EGFR in Cancer Research
article

86P Payload-driven fatal toxicity signals of antibody–drug conjugates in endometrial cancer: A FAERS disproportionality analysis

E.H. Hasanin
article en

Abstract

Antibody–drug conjugates (ADCs) have expanded therapeutic options in gynecologic malignancies, including endometrial cancer, but are associated with potentially serious and fatal toxicities. This study evaluates the association between ADCs and adverse event profiles, including fatal outcomes, using the FDA Adverse Event Reporting System.

ESMO OpenVol. 11
University of Tripoli (LY)
Good health and well-being
Openalex Percentile: Top 8%
HER2/EGFR in Cancer Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

86P Payload-driven fatal toxicity signals of antibody–drug conjugates in endometrial cancer: A FAERS disproportionality analysis — E.H. Hasanin · ESMO Open (2026) | TGRS Research Map | TGRS