The role of estimated muscle power from a sit-to-stand test in determining frailty in community-dwelling older adults

INTRODUCTION: This study explored the usefulness of estimated lower-limb muscle power, derived from the 5-times sit-to-stand (5xSTS) test, for identifying frailty among community-dwelling older adults in Ireland. METHODS: Data from Wave 3 of The Irish Longitudinal Study on Ageing (TILDA) were analysed, focusing on adults aged 50 years and older. Muscle power was estimated using a standardised equation from the five-time sit-to-stand (5xSTS) test, incorporating body height, mass, and chair height. Frailty status was classified using an Index, according to established criteria. Logistic regression models assessed the predictive capacity of muscle power relative to 5xSTS. Thresholds for frailty risk were explored through Receiver Operating Curves and Locally Weighted Scatterplot Smoothing. RESULTS: Findings reveal a decline in muscle power with advancing age, more pronounced in females and frail individuals. Muscle power estimates showed moderate agreement with frailty status, with sensitivity and specificity comparable to those of the 5xSTS. Muscle power less than 2.5 Watt·kg -¹ in males and 2.08 Watt·kg -¹ in females was associated with increased frailty risk, consistent with other studies. Overall power estimation showed a predictive performance similar to that of traditional assessments such as Timed Up and Go, supporting its utility in clinical and community settings. CONCLUSION: Estimated muscle power derived from the 5xSTS test is a practical, reliable tool for early identification of frailty among older adults. Its accessibility and predictive validity suggest it could complement existing clinical assessments but not replace them.

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Journal
PLoS ONE
Published
2026-07-02
DOI
https://doi.org/10.1371/journal.pone.0352160
Primary Topic
Frailty in Older Adults
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article
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article

The role of estimated muscle power from a sit-to-stand test in determining frailty in community-dwelling older adults

Cillin Condon, Fearghal P. Behan, Sean McAuliffe, Roman Romero-Ortuno et al.
PLoS ONE
Frailty in Older Adults
article

The role of estimated muscle power from a sit-to-stand test in determining frailty in community-dwelling older adults

Cillin Condon, Fearghal P. Behan, Sean McAuliffe, Roman Romero-Ortuno, Eleanor Fallon
article en

Abstract

INTRODUCTION: This study explored the usefulness of estimated lower-limb muscle power, derived from the 5-times sit-to-stand (5xSTS) test, for identifying frailty among community-dwelling older adults in Ireland. METHODS: Data from Wave 3 of The Irish Longitudinal Study on Ageing (TILDA) were analysed, focusing on adults aged 50 years and older. Muscle power was estimated using a standardised equation from the five-time sit-to-stand (5xSTS) test, incorporating body height, mass, and chair height. Frailty status was classified using an Index, according to established criteria. Logistic regression models assessed the predictive capacity of muscle power relative to 5xSTS. Thresholds for frailty risk were explored through Receiver Operating Curves and Locally Weighted Scatterplot Smoothing. RESULTS: Findings reveal a decline in muscle power with advancing age, more pronounced in females and frail individuals. Muscle power estimates showed moderate agreement with frailty status, with sensitivity and specificity comparable to those of the 5xSTS. Muscle power less than 2.5 Watt·kg -¹ in males and 2.08 Watt·kg -¹ in females was associated with increased frailty risk, consistent with other studies. Overall power estimation showed a predictive performance similar to that of traditional assessments such as Timed Up and Go, supporting its utility in clinical and community settings. CONCLUSION: Estimated muscle power derived from the 5xSTS test is a practical, reliable tool for early identification of frailty among older adults. Its accessibility and predictive validity suggest it could complement existing clinical assessments but not replace them.

PLoS ONEVol. 21(7)
Trinity College Dublin (IE), University of Limerick (IE)
Openalex Percentile: Top 10%
Frailty in Older Adults
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The role of estimated muscle power from a sit-to-stand test in determining frailty in community-dwelling older adults — Cillin Condon, Fearghal P. Behan, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS