31P Post-chemoradiation HPV ctDNA clearance as a biomarker of residual disease and relapse in locally advanced cervical cancer: A systematic review and meta-analysis
In locally advanced cervical cancer (LACC), conventional post-chemoradiation assessment cannot reliably distinguish true response from occult residual disease. Human papillomavirus circulating tumour DNA (HPV ctDNA) is a promising biomarker of treatment response. We performed a systematic review and meta-analysis to determine whether failure of HPV ctDNA clearance after definitive chemoradiation predicts residual disease and relapse.
Authors
- K. Dinas
- S. Petousis
- L. Basmpana
- C. Margioula-Siarkou
Institutions
- National and Kapodistrian University of Athens (GR)
- Aristotle University of Thessaloniki (GR)
- Ippokrateio General Hospital of Thessaloniki (GR)
Publication Details
- Journal
- ESMO Open
- Published
- 2026-07-01
- DOI
- https://doi.org/10.1016/j.esmoop.2026.108057
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00