<scp>GWAS</scp> of Second‐Generation Antihistamine Use: Locus Specificity and Highlighted Signalling Pathways
Summary Four of 67 loci were specific to antihistamine use; most overlapped inflammatory disease susceptibility. Genetic variation enriched in IL‐2 cytokine, JAK–STAT pathway genes shared by allergy and autoimmunity.
Authors
- T. Harju
- Jukka Partanen (ORCID: https://orcid.org/0000-0001-6681-4734)
- Thijs Feuth (ORCID: https://orcid.org/0000-0001-6691-556X)
- Riitta Lahesmaa (ORCID: https://orcid.org/0000-0002-4782-9567)
- Tarja Laitinen (ORCID: https://orcid.org/0009-0003-7062-8629)
- Vesa P. Hytönen (ORCID: https://orcid.org/0000-0002-9357-1480)
- Elmo Saarentaus (ORCID: https://orcid.org/0000-0002-8475-7187)
- Hannu Kankaanranta (ORCID: https://orcid.org/0000-0001-5258-0906)
- Paula Kauppi (ORCID: https://orcid.org/0000-0002-1065-330X)
- Inna Starskaia (ORCID: https://orcid.org/0000-0003-4349-439X)
- Iida Vähätalo (ORCID: https://orcid.org/0000-0003-0962-8446)
- Aarno V. Palotie (ORCID: https://orcid.org/0000-0002-2527-5874)
- M. Pelkonen
- F FinnGen
- M Niemi
- S. Ruotsalainen
Institutions
- Åbo Akademi University (FI)
- University of Helsinki (FI)
- Tampere University of Applied Sciences (FI)
- University of Turku (FI)
- Tampere University (FI)
- Seinäjoki University of Applied Sciences (FI)
- Turku Centre for Computer Science (FI)
- Oulu University Hospital (FI)
- Helsinki University Hospital (FI)
- Finnish Red Cross (FI)
- Turku University Hospital (FI)
- Kuopio University Hospital (FI)
- Tampere University (FI)
- Institute for Molecular Medicine Finland (FI)
- Fimlab (Finland) (FI)
- Hospital District of Helsinki and Uusimaa (FI)
- University of Gothenburg (SE)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2026-07-02
- DOI
- https://doi.org/10.1111/cea.70382
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AbbVie
- Business Finland