Asymmetric Hydrophosphination of Quinolinones and Chromones Catalyzed by Chiral Phosphoric Acid
Here, we report the first highly efficient and enantioselective hydrophosphination of quinolinones and chromones catalyzed by chiral phosphoric acids, affording C2-stereogenic phosphorus derivatives in good yields and high enantioselectivities. Notably, these products serve as versatile synthetic intermediates that can be readily elaborated to a range of valuable phosphorus-containing molecules.
Authors
- Guiyong Wang (ORCID: https://orcid.org/0000-0002-0265-8207)
- Zhifeng Ma (ORCID: https://orcid.org/0000-0001-6084-2371)
- Yafei Guo (ORCID: https://orcid.org/0000-0001-8720-3887)
- B Q Fan
- Jiuling Li
- Rui Yang
- Shengrong Chen
Institutions
- Minzu University of China (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-07-02
- DOI
- https://doi.org/10.1021/acs.orglett.6c02232
- Primary Topic
- Organophosphorus compounds synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Yunnan Provincial Department of Education
- Yunnan Provincial Science and Technology Department