Endothelial-to-mesenchymal transition derived fibronectin mediates pulmonary fibrosis in mice following chronic exposure to ozone-oxidized 6PPD
-6PPD-induced pulmonary fibrosis, providing new insights into the health risks of tire-wear-related transformation products and potential vascular-targeted therapeutic strategies.
Authors
- Yi Yang (ORCID: https://orcid.org/0000-0002-4091-8532)
- S Q Wang
- Xianjie Li (ORCID: https://orcid.org/0000-0002-2749-5352)
- Chuanze Zhang
- Ping Guo (ORCID: https://orcid.org/0000-0003-0096-4814)
- Caixia Wu
- Zhizun Deng
- Yanxi Li
- Shen Chen
- Han Wang
- Ping Yang
- Ming Li
Institutions
- Sun Yat-sen University (CN)
- Gunma University (JP)
- Liaocheng University (CN)
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Guangdong Academy of Sciences (CN)
- South China Institute Of Environmental Sciences (CN)
- Shandong First Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2026-07-01
- DOI
- https://doi.org/10.1016/j.ecoenv.2026.120457
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Japan Society for the Promotion of Science
- Guangdong Academy of Sciences