Esophageal Bleeding and Radiational Esophagitis Presenting as Acute Gastroesophageal Junction Obstruction

Acute gastroesophageal junction (GEJ) obstruction is an uncommon condition which can raise concern for malignancy. We report a case of spontaneous esophageal bleeding of a patient on chronic anticoagulation who received radiation therapy 4 months prior, presenting with sudden onset intractable nausea, vomiting and abdominal pain. Imaging demonstrated marked esophageal dilation with distal obstruction. Endoscopy revealed a large friable, near-obstructing esophageal mass with extensive clot burden. Repeated biopsies showed necrotic debris, inflammation, and fungal elements without malignancy. Endoscopic removal led to complete symptom resolution.

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Publication Details

Journal
Gastro Hep Advances
Published
2026-07-01
DOI
https://doi.org/10.1016/j.gastha.2026.101044
Primary Topic
Effects of Radiation Exposure
Type
article
Field-Weighted Citation Impact
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article

Esophageal Bleeding and Radiational Esophagitis Presenting as Acute Gastroesophageal Junction Obstruction

Yilin Song, Ivan Berezowski, Nisha Ramamurthy, Romy Chamoun et al.
Gastro Hep Advances
Effects of Radiation Exposure
article

Esophageal Bleeding and Radiational Esophagitis Presenting as Acute Gastroesophageal Junction Obstruction

Yilin Song, Ivan Berezowski, Nisha Ramamurthy, Romy Chamoun, Huimin Yu
article en

Abstract

Acute gastroesophageal junction (GEJ) obstruction is an uncommon condition which can raise concern for malignancy. We report a case of spontaneous esophageal bleeding of a patient on chronic anticoagulation who received radiation therapy 4 months prior, presenting with sudden onset intractable nausea, vomiting and abdominal pain. Imaging demonstrated marked esophageal dilation with distal obstruction. Endoscopy revealed a large friable, near-obstructing esophageal mass with extensive clot burden. Repeated biopsies showed necrotic debris, inflammation, and fungal elements without malignancy. Endoscopic removal led to complete symptom resolution.

Gastro Hep Advances
University of Maryland, Baltimore (US), George Washington University Hospital (US), Mayo Clinic (US), George Washington University (US), Mayo Clinic in Arizona (US), University of Maryland Medical Center Midtown Campus (US), Mayo Clinic in Florida (US)
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Openalex Percentile: Top 7%
Effects of Radiation Exposure
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