Esophageal Bleeding and Radiational Esophagitis Presenting as Acute Gastroesophageal Junction Obstruction
Acute gastroesophageal junction (GEJ) obstruction is an uncommon condition which can raise concern for malignancy. We report a case of spontaneous esophageal bleeding of a patient on chronic anticoagulation who received radiation therapy 4 months prior, presenting with sudden onset intractable nausea, vomiting and abdominal pain. Imaging demonstrated marked esophageal dilation with distal obstruction. Endoscopy revealed a large friable, near-obstructing esophageal mass with extensive clot burden. Repeated biopsies showed necrotic debris, inflammation, and fungal elements without malignancy. Endoscopic removal led to complete symptom resolution.
Authors
- Yilin Song (ORCID: https://orcid.org/0000-0002-9664-2029)
- Ivan Berezowski (ORCID: https://orcid.org/0000-0003-4406-7517)
- Nisha Ramamurthy
- Romy Chamoun
- Huimin Yu
Institutions
- University of Maryland, Baltimore (US)
- George Washington University Hospital (US)
- Mayo Clinic (US)
- George Washington University (US)
- Mayo Clinic in Arizona (US)
- University of Maryland Medical Center Midtown Campus (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Gastro Hep Advances
- Published
- 2026-07-01
- DOI
- https://doi.org/10.1016/j.gastha.2026.101044
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00