Acquired cystic disease-associated renal cell carcinoma mimicking gallbladder carcinoma

A 58-year-old woman on long-term hemodialysis underwent computed tomography for diabetic foot gangrene, which revealed a mass adjacent to the gallbladder, suggesting gallbladder carcinoma. Magnetic resonance imaging also suggested a gallbladder tumor. At laparotomy, the lesion was found to originate from the right kidney, and right nephrectomy was performed. Histopathological and immunohistochemical findings (AMACR+, CD10+, CK7−) confirmed acquired cystic disease-associated renal cell carcinoma (ACD-RCC). ACD-RCC may present with atypical imaging findings and mimic adjacent organ malignancies in patients on dialysis.

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Publication Details

Journal
Urology Case Reports
Published
2026-07-01
DOI
https://doi.org/10.1016/j.eucr.2026.103526
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
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Acquired cystic disease-associated renal cell carcinoma mimicking gallbladder carcinoma

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Urology Case Reports
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Acquired cystic disease-associated renal cell carcinoma mimicking gallbladder carcinoma

Yoshihiro Kawaguchi, Futoshi Morokuma, Mai Nonaka, Daisuke Mori, Atsushi Miyoshi
article en

Abstract

A 58-year-old woman on long-term hemodialysis underwent computed tomography for diabetic foot gangrene, which revealed a mass adjacent to the gallbladder, suggesting gallbladder carcinoma. Magnetic resonance imaging also suggested a gallbladder tumor. At laparotomy, the lesion was found to originate from the right kidney, and right nephrectomy was performed. Histopathological and immunohistochemical findings (AMACR+, CD10+, CK7−) confirmed acquired cystic disease-associated renal cell carcinoma (ACD-RCC). ACD-RCC may present with atypical imaging findings and mimic adjacent organ malignancies in patients on dialysis.

Urology Case Reports
Saga-Ken Medical Centre Koseikan (JP), DMG Mori (Japan) (JP)
Good health and well-being
Openalex Percentile: Top 6%
Cholangiocarcinoma and Gallbladder Cancer Studies
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