Reconsidering Cancer Therapy through the Lens of Biomolecular Condensates
Biomolecular condensates formed via phase separation are emerging targets for pharmacologic or genetic manipulation for cancer therapy. In this commentary, we envisage that further deciphering the composition and the physicochemical properties of oncogenic condensates will provide unprecedented opportunities to develop novel strategies for cancer chemotherapy and immunotherapy.
Authors
- Yuanzhong Wu (ORCID: https://orcid.org/0000-0002-3577-7069)
- Q H Yin
- Jiawen Feng (ORCID: https://orcid.org/0000-0001-6303-8338)
- Kaiqiang You (ORCID: https://orcid.org/0000-0002-5038-1185)
- Tingting Li (ORCID: https://orcid.org/0000-0003-4266-0317)
Institutions
- Sun Yat-sen University (CN)
- Peking University (CN)
- Sichuan University (CN)
- National Health and Family Planning Commission (CN)
- Ministry of Education (ME)
- National Clinical Research (US)
- Stomatology Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- Cancer Discovery
- Published
- 2026-07-01
- DOI
- https://doi.org/10.1158/2159-8290.cd-25-2088
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00