Ulipristal acetate for use in medical management of early pregnancy loss: a pilot feasibility study
Mifepristone availability for medical management of early pregnancy loss (EPL) is limited in some settings. We report a single site, single arm pilot of ulipristal acetate for EPL management as an alternative to mifepristone. While recruitment was challenging, all participants adhered to study protocol and passed their pregnancy without additional intervention. TRIAL REGISTRATION: ClinicalTrials.gov (ID NCT05216952), registered January 19, 2022, https//clinicaltrials.gov/study/NCT05216952.
Authors
- Jennifer H. Tang (ORCID: https://orcid.org/0000-0003-4238-2791)
- Jessica E. Morse (ORCID: https://orcid.org/0000-0002-1383-1749)
- Amy G. Bryant (ORCID: https://orcid.org/0000-0001-7066-6615)
- Jill M Hagey
Institutions
- University of North Carolina at Chapel Hill (US)
- Duke University (US)
- University of North Carolina Hospitals (US)
- Duke Medical Center (US)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2026-07-02
- DOI
- https://doi.org/10.1186/s12884-026-09485-4
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Society of Family Planning
- School of Medicine, University of North Carolina at Chapel Hill
- North Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill