Fifty years of SSRI-related oral side effects: A call for interprofessional collaboration

The oral side effects of selective serotonin reuptake inhibitors (SSRIs) include xerostomia, gingival bleeding, burning mouth syndrome, bruxism, and temporomandibular disorders (TMD), impacting the quality of life (QoL). These stomatognathic diseases are often overlooked in clinical practice. This comment advocates interprofessional relations among physicians, pharmacists and dentists to improve the recognition, prevention and management of SSRI-related oral side effects.

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Publication Details

Journal
Dental and Medical Problems
Published
2026-06-30
DOI
https://doi.org/10.17219/dmp/217607
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00
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article

Fifty years of SSRI-related oral side effects: A call for interprofessional collaboration

Frank Lobbezoo, Anne-Fleur H. Lobbezoo, Pauline Marie-Julie Lobbezoo, Agnes Maria Lobbezoo-Scholte et al.
Dental and Medical Problems
Salivary Gland Disorders and Functions
article

Fifty years of SSRI-related oral side effects: A call for interprofessional collaboration

Frank Lobbezoo, Anne-Fleur H. Lobbezoo, Pauline Marie-Julie Lobbezoo, Agnes Maria Lobbezoo-Scholte, Rosanne Veronique Lobbezoo
article en

Abstract

The oral side effects of selective serotonin reuptake inhibitors (SSRIs) include xerostomia, gingival bleeding, burning mouth syndrome, bruxism, and temporomandibular disorders (TMD), impacting the quality of life (QoL). These stomatognathic diseases are often overlooked in clinical practice. This comment advocates interprofessional relations among physicians, pharmacists and dentists to improve the recognition, prevention and management of SSRI-related oral side effects.

Dental and Medical ProblemsVol. 63(3)
Malmö University (SE), Utrecht University (NL), Academic Center for Dentistry Amsterdam (NL), University Medical Center Utrecht (NL), Parnassia Groep (NL), St. Antonius Ziekenhuis (NL)
Openalex Percentile: Top 7%
Salivary Gland Disorders and Functions
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