Oncological Safety of Minimally Invasive Multivisceral Resection for cT4b Rectal Cancer: A Multicenter Comparison With Open Surgery

BACKGROUND/AIM: Minimally invasive surgery (MIS), including laparoscopic and robotic approaches, is increasingly used for rectal cancer but evidence of multivisceral resection (MVR) for cT4b disease by MIS is limited. This study compared short- and long-term outcomes between patients who underwent MIS or open MVR for advanced rectal cancer. PATIENTS AND METHODS: We retrospectively analyzed 32 patients with cT4b rectal cancer who underwent rectal resection with MVR at six institutions between 2011 and 2023 (open, n=9; MIS, n=23). Operative invasiveness, postoperative complications, and 3-year survival were evaluated. RESULTS: <0.0001). After excluding those with stage IV disease (open, n=9; MIS, n=20), pathological outcomes and 3-year survival did not differ between groups. CONCLUSION: MIS may reduce invasiveness without compromising oncological outcomes in selected patients with cT4b rectal cancer requiring MVR.

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Journal
In Vivo
Published
2026-06-30
DOI
https://doi.org/10.21873/invivo.14375
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
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article

Oncological Safety of Minimally Invasive Multivisceral Resection for cT4b Rectal Cancer: A Multicenter Comparison With Open Surgery

Kentaro Nonaka, Sho Nambara, Tetsuro Kawazoe, Shinichiro Ikeda et al.
In Vivo
Colorectal Cancer Surgical Treatments
article

Oncological Safety of Minimally Invasive Multivisceral Resection for cT4b Rectal Cancer: A Multicenter Comparison With Open Surgery

Kentaro Nonaka, Sho Nambara, Tetsuro Kawazoe, Shinichiro Ikeda, Koji Ando, Ryota Nakanishi, Tomoharu Yoshizumi, Kippei Ohgaki, Eiji Oki, Yoshihiko Fujinaka, Hirofumi Hasuda, Yuta Kasagi, Tomonori Nakanoko, Masahiko Sugiyama, Tomoya Harima, DAISUKE YOSHIDA, YASUO TSUDA
article en

Abstract

BACKGROUND/AIM: Minimally invasive surgery (MIS), including laparoscopic and robotic approaches, is increasingly used for rectal cancer but evidence of multivisceral resection (MVR) for cT4b disease by MIS is limited. This study compared short- and long-term outcomes between patients who underwent MIS or open MVR for advanced rectal cancer. PATIENTS AND METHODS: We retrospectively analyzed 32 patients with cT4b rectal cancer who underwent rectal resection with MVR at six institutions between 2011 and 2023 (open, n=9; MIS, n=23). Operative invasiveness, postoperative complications, and 3-year survival were evaluated. RESULTS: <0.0001). After excluding those with stage IV disease (open, n=9; MIS, n=20), pathological outcomes and 3-year survival did not differ between groups. CONCLUSION: MIS may reduce invasiveness without compromising oncological outcomes in selected patients with cT4b rectal cancer requiring MVR.

In VivoVol. 40(4)
Kyushu University (JP), National Kyushu Medical Center (JP), National Hospital Organization Kyushu Cancer Center (JP), Kyushu University Hospital (JP), Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers (JP), Beppu Medical Center (JP), Aso Iizuka Hospital (JP)
Good health and well-being
Openalex Percentile: Top 8%
Colorectal Cancer Surgical Treatments
DOIOpen Access PDFOpenAlex
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