Automatic Phase and Sequence Identification in Gd-EOB-DTPA–Enhanced Liver MRI Using Deep Convolutional and Sequential Learning

The purpose of this study is to develop and validate a deep learning model for automatic identification of acquisition sequences (including T1-weighted sequences with various dynamic contrast-enhanced phases and other auxiliary sequences) in gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced liver MRI, enabling automated examination-level data curation. This retrospective study included internal Gd-EOB-DTPA-enhanced liver MRI examinations acquired at our institution between June 2018 and May 2020, with independent external test datasets from three additional institutions. Each examination comprised multiple dynamic contrast-enhanced phases and auxiliary sequences, resulting in 13 predefined label categories. A deep learning pipeline was constructed using a convolutional neural network (ConvNeXt) for feature extraction, followed by sequential models (gated recurrent unit [GRU]-based or transformer-based) to model temporal relationships across series. Models were trained using series-level 3D image volumes without reliance on textual Digital Imaging and Communications in Medicine metadata. Model selection was performed on a validation set. Performance was evaluated on internal and external test sets using examination-level accuracy, complete-correct rate, and category-level accuracy. Sequential modeling substantially improved performance compared with a convolution-only baseline. The ConvNeXt + GRU model achieved the highest examination-level accuracy and was selected for final evaluation. Dynamic contrast-enhanced phases were identified with high accuracy across datasets. Reduced performance on the external test set was mainly observed for auxiliary sequences with high inter-institutional variability, particularly in T2-weighted imaging. The proposed framework enables accurate automatic identification of dynamic phases and auxiliary sequences in Gd-EOB-DTPA-enhanced liver MRI, supporting robust examination-level data organization in multicenter studies.

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Publication Details

Journal
Journal of Imaging Informatics in Medicine
Published
2026-06-30
DOI
https://doi.org/10.1007/s10278-026-02080-1
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
0.00

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article

Automatic Phase and Sequence Identification in Gd-EOB-DTPA–Enhanced Liver MRI Using Deep Convolutional and Sequential Learning

Tomomi Takenaga, Tomohiro Kikuchi, Osamu Abe, T. Yoshikawa et al.
Journal of Imaging Informatics in Medicine
Radiomics and Machine Learning in Medical Imaging
article

Automatic Phase and Sequence Identification in Gd-EOB-DTPA–Enhanced Liver MRI Using Deep Convolutional and Sequential Learning

Tomomi Takenaga, Tomohiro Kikuchi, Osamu Abe, T. Yoshikawa, Shouhei Hanaoka, Yukihiro Nomura
article en

Abstract

The purpose of this study is to develop and validate a deep learning model for automatic identification of acquisition sequences (including T1-weighted sequences with various dynamic contrast-enhanced phases and other auxiliary sequences) in gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced liver MRI, enabling automated examination-level data curation. This retrospective study included internal Gd-EOB-DTPA-enhanced liver MRI examinations acquired at our institution between June 2018 and May 2020, with independent external test datasets from three additional institutions. Each examination comprised multiple dynamic contrast-enhanced phases and auxiliary sequences, resulting in 13 predefined label categories. A deep learning pipeline was constructed using a convolutional neural network (ConvNeXt) for feature extraction, followed by sequential models (gated recurrent unit [GRU]-based or transformer-based) to model temporal relationships across series. Models were trained using series-level 3D image volumes without reliance on textual Digital Imaging and Communications in Medicine metadata. Model selection was performed on a validation set. Performance was evaluated on internal and external test sets using examination-level accuracy, complete-correct rate, and category-level accuracy. Sequential modeling substantially improved performance compared with a convolution-only baseline. The ConvNeXt + GRU model achieved the highest examination-level accuracy and was selected for final evaluation. Dynamic contrast-enhanced phases were identified with high accuracy across datasets. Reduced performance on the external test set was mainly observed for auxiliary sequences with high inter-institutional variability, particularly in T2-weighted imaging. The proposed framework enables accurate automatic identification of dynamic phases and auxiliary sequences in Gd-EOB-DTPA-enhanced liver MRI, supporting robust examination-level data organization in multicenter studies.

Journal of Imaging Informatics in Medicine
Jichi Medical University (JP), Chiba University (JP), University of Tokyo Hospital (JP)
University of Tokyo, Japan Society for the Promotion of Science
Openalex Percentile: Top 7%
Radiomics and Machine Learning in Medical Imaging
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