Automatic Phase and Sequence Identification in Gd-EOB-DTPA–Enhanced Liver MRI Using Deep Convolutional and Sequential Learning
The purpose of this study is to develop and validate a deep learning model for automatic identification of acquisition sequences (including T1-weighted sequences with various dynamic contrast-enhanced phases and other auxiliary sequences) in gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced liver MRI, enabling automated examination-level data curation. This retrospective study included internal Gd-EOB-DTPA-enhanced liver MRI examinations acquired at our institution between June 2018 and May 2020, with independent external test datasets from three additional institutions. Each examination comprised multiple dynamic contrast-enhanced phases and auxiliary sequences, resulting in 13 predefined label categories. A deep learning pipeline was constructed using a convolutional neural network (ConvNeXt) for feature extraction, followed by sequential models (gated recurrent unit [GRU]-based or transformer-based) to model temporal relationships across series. Models were trained using series-level 3D image volumes without reliance on textual Digital Imaging and Communications in Medicine metadata. Model selection was performed on a validation set. Performance was evaluated on internal and external test sets using examination-level accuracy, complete-correct rate, and category-level accuracy. Sequential modeling substantially improved performance compared with a convolution-only baseline. The ConvNeXt + GRU model achieved the highest examination-level accuracy and was selected for final evaluation. Dynamic contrast-enhanced phases were identified with high accuracy across datasets. Reduced performance on the external test set was mainly observed for auxiliary sequences with high inter-institutional variability, particularly in T2-weighted imaging. The proposed framework enables accurate automatic identification of dynamic phases and auxiliary sequences in Gd-EOB-DTPA-enhanced liver MRI, supporting robust examination-level data organization in multicenter studies.
Authors
- Tomomi Takenaga (ORCID: https://orcid.org/0000-0001-7198-1588)
- Tomohiro Kikuchi (ORCID: https://orcid.org/0000-0002-4222-4569)
- Osamu Abe (ORCID: https://orcid.org/0000-0002-1180-2629)
- T. Yoshikawa (ORCID: https://orcid.org/0000-0002-1924-5468)
- Shouhei Hanaoka (ORCID: https://orcid.org/0000-0002-7496-1651)
- Yukihiro Nomura (ORCID: https://orcid.org/0000-0001-6471-9936)
Institutions
- Jichi Medical University (JP)
- Chiba University (JP)
- University of Tokyo Hospital (JP)
Publication Details
- Journal
- Journal of Imaging Informatics in Medicine
- Published
- 2026-06-30
- DOI
- https://doi.org/10.1007/s10278-026-02080-1
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Tokyo
- Japan Society for the Promotion of Science