Peri-operative nutrition in femoral neck fracture arthroplasty: a pragmatic framework to mitigate dual-hit catabolism and improve outcomes
Femoral neck fracture patients represent one of the most metabolically vulnerable populations undergoing total hip arthroplasty, with malnutrition prevalence frequently exceeding 40–50%. • Acute trauma, enforced fasting, inflammation and comorbidity amplify the surgical stress response, accelerating protein catabolism, immune dysfunction and muscle loss. • Malnutrition in femoral neck fracture patients is independently associated with increased mortality, infection, prolonged hospital stay, delayed mobilisation and institutionalisation. • Unlike elective arthroplasty, opportunities for pre-operative optimisation are limited, making early identification and aggressive peri-operative nutritional support critical. • A phase-specific nutritional framework—focused on rapid screening, intra-operative metabolic protection and early post-operative feeding—offers a pragmatic, low-cost strategy to improve outcomes, particularly in LMIC settings.
Authors
- Winifred Mukiibi
- Nkhodiseni Sikhauli (ORCID: https://orcid.org/0000-0002-0862-8615)
- Dyllan Brett Geldenhuys (ORCID: https://orcid.org/0009-0004-3312-7806)
- Leonard Muhango
- J R T Pietrzak
- Nena Elebo
Institutions
- University of the Witwatersrand (ZA)
Publication Details
- Journal
- Orthopedic Reviews
- Published
- 2026-06-30
- DOI
- https://doi.org/10.52965/001c.163301
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00