What makes a good diagnostic tool: An elicitation using a Multi-Criteria Decision Analysis framework
Diagnostic tools are essential to health-related decision-making for animals, humans and the environment. However, defining what constitutes a good diagnostic remains challenging. This study applied a Multi-Criteria Decision Analysis (MCDA) framework to identify and weight key attributes of diagnostic tools for infectious diseases. A workshop conducted as part of the EU Partnership on Animal Health and Welfare (EU PAHW), engaging experts to define, discuss, and score evaluation criteria. Six core criteria were identified: Performance, Data Interpretation, Cost, Speed/Timeliness, Ease of Testing, and Generality. Performance was rated as the most important attribute, followed by Data Interpretation and Cost. These findings provide an evidence-based framework for assessing diagnostics and prioritising development efforts, and the approach can support One Health strategies for improving diagnostic accessibility and effectiveness.
Authors
- Mahbod Entezami (ORCID: https://orcid.org/0000-0003-1854-3209)
- Pikka Jokelainen (ORCID: https://orcid.org/0000-0002-3035-5094)
- Jo Widdicombe (ORCID: https://orcid.org/0000-0003-1266-5395)
- Roberto Marcello La Ragione (ORCID: https://orcid.org/0000-0001-5861-613X)
- Anne Sofie Hammer (ORCID: https://orcid.org/0000-0001-9690-2225)
- Ana Cristina Ferreira (ORCID: https://orcid.org/0000-0002-9607-7576)
- Joaquín M. Prada (ORCID: https://orcid.org/0000-0003-4699-5931)
- Anna K. Fotaki
Institutions
- Statens Serum Institut (DK)
- University of Copenhagen (DK)
- University of Helsinki (FI)
- Estonian University of Life Sciences (EE)
- University of Surrey (GB)
- Instituto Nacional de Investigação Agrária e Veterinária (PT)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2026-06-30
- DOI
- https://doi.org/10.5281/zenodo.21066420
- Primary Topic
- Zoonotic diseases and public health
- Type
- preprint
Funders
- European Commission