Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Presenting as Cortical Encephalitis in A Patient with Crohn’s Disease Receiving Anti-Tumor Necrosis Factor Therapy

A 28-year-old man with Crohn’s disease receiving infliximab developed focal motor seizures with unilateral cortical hyperintensity on brain magnetic resonance imaging and serum myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G positivity, consistent with MOG antibody-associated disease (MOGAD) presenting as cortical encephalitis. His symptoms improved after corticosteroid therapy. MOGAD should be considered in patients receiving anti-tumor necrosis factor therapy who develop new-onset cortical manifestations.

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Publication Details

Journal
Journal of Multiple Sclerosis and Neuroimmunology
Published
2026-06-30
DOI
https://doi.org/10.59578/jmsni.2026.17.1.7-10
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Presenting as Cortical Encephalitis in A Patient with Crohn’s Disease Receiving Anti-Tumor Necrosis Factor Therapy

Jin Myoung Seok, Jee Hyun Kim, Joo Yeon Lee
Journal of Multiple Sclerosis and Neuroimmunology
Autoimmune Neurological Disorders and Treatments
article

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Presenting as Cortical Encephalitis in A Patient with Crohn’s Disease Receiving Anti-Tumor Necrosis Factor Therapy

Jin Myoung Seok, Jee Hyun Kim, Joo Yeon Lee
article en

Abstract

A 28-year-old man with Crohn’s disease receiving infliximab developed focal motor seizures with unilateral cortical hyperintensity on brain magnetic resonance imaging and serum myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G positivity, consistent with MOG antibody-associated disease (MOGAD) presenting as cortical encephalitis. His symptoms improved after corticosteroid therapy. MOGAD should be considered in patients receiving anti-tumor necrosis factor therapy who develop new-onset cortical manifestations.

Journal of Multiple Sclerosis and NeuroimmunologyVol. 17(1)
Ewha Womans University (KR)
Good health and well-being
Openalex Percentile: Top 8%
Autoimmune Neurological Disorders and Treatments
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