Rare but Important Peripheral Neuropathies Around the Shoulder Joint

Peripheral neuropathies around the shoulder joint are relatively rare but clinically significant, as delayed diagnosis can lead to serious functional impairment.This review summarizes the pathophysiology, clinical presentation, diagnosis, treatment, and prognosis of three important but uncommon neuropathic conditions around the shoulder joint-(1) hourglass-like constriction neuropathy, (2) compressive neuropathy caused by paralabral cysts, and (3) perineural tumor spread-based on a literature review and clinical experience.The aim of this review is to reduce misdiagnosis and facilitate appropriate management by actively considering these rare neuropathies in patients presenting with unexplained shoulder pain and muscle weakness.

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Publication Details

Journal
Clinical Pain
Published
2026-06-30
DOI
https://doi.org/10.35827/cp.2026.25.1.27
Primary Topic
Peripheral Nerve Disorders
Type
article
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article

Rare but Important Peripheral Neuropathies Around the Shoulder Joint

Yu Jin Im
Clinical Pain
Peripheral Nerve Disorders
article

Rare but Important Peripheral Neuropathies Around the Shoulder Joint

Yu Jin Im
article en

Abstract

Peripheral neuropathies around the shoulder joint are relatively rare but clinically significant, as delayed diagnosis can lead to serious functional impairment.This review summarizes the pathophysiology, clinical presentation, diagnosis, treatment, and prognosis of three important but uncommon neuropathic conditions around the shoulder joint-(1) hourglass-like constriction neuropathy, (2) compressive neuropathy caused by paralabral cysts, and (3) perineural tumor spread-based on a literature review and clinical experience.The aim of this review is to reduce misdiagnosis and facilitate appropriate management by actively considering these rare neuropathies in patients presenting with unexplained shoulder pain and muscle weakness.

Clinical PainVol. 25(1)
Samsung Medical Center (KR), Sungkyunkwan University (KR)
Good health and well-being
Openalex Percentile: Top 7%
Peripheral Nerve Disorders
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Rare but Important Peripheral Neuropathies Around the Shoulder Joint — Yu Jin Im · Clinical Pain (2026) | TGRS Research Map | TGRS