A Rare Case Report of Cutaneous T-cell Lymphoma in an Adolescent Female

Cutaneous T-cell lymphoma (CTCL) is a rare lymphoproliferative disorder and is infrequently encountered in adolescents.We report a 16-yearold female who presented with prolonged low-grade fever followed by progressive violaceous papulonodular lesions involving the face and extremities, accompanied by lymphadenopathy and generalized edema.Laboratory investigations revealed pancytopenia, hypoalbuminemia, and hepatosplenomegaly, with infectious and autoimmune causes excluded.Skin biopsy showed dense dermal infiltration by atypical lymphoid cells.Immunohistochemistry confirmed a T-cell phenotype with positivity for CD3, CD5, and CD30, and absence of B-cell markers, with a low proliferative index.Bone marrow examination revealed no malignant infiltration, supporting a primary cutaneous origin.The patient was managed conservatively and referred for specialized care.

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Publication Details

Journal
Bengal Physician Journal
Published
2026-06-30
DOI
https://doi.org/10.5005/jp-journals-10070-8147
Primary Topic
Cutaneous lymphoproliferative disorders research
Type
article
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article

A Rare Case Report of Cutaneous T-cell Lymphoma in an Adolescent Female

Shilpi Biswas, Robert Ekka, Debasis Chakrabarti, Triparna Bhadra et al.
Bengal Physician Journal
Cutaneous lymphoproliferative disorders research
article

A Rare Case Report of Cutaneous T-cell Lymphoma in an Adolescent Female

Shilpi Biswas, Robert Ekka, Debasis Chakrabarti, Triparna Bhadra, Utso Aich, Mandira Mondal
article en

Abstract

Cutaneous T-cell lymphoma (CTCL) is a rare lymphoproliferative disorder and is infrequently encountered in adolescents.We report a 16-yearold female who presented with prolonged low-grade fever followed by progressive violaceous papulonodular lesions involving the face and extremities, accompanied by lymphadenopathy and generalized edema.Laboratory investigations revealed pancytopenia, hypoalbuminemia, and hepatosplenomegaly, with infectious and autoimmune causes excluded.Skin biopsy showed dense dermal infiltration by atypical lymphoid cells.Immunohistochemistry confirmed a T-cell phenotype with positivity for CD3, CD5, and CD30, and absence of B-cell markers, with a low proliferative index.Bone marrow examination revealed no malignant infiltration, supporting a primary cutaneous origin.The patient was managed conservatively and referred for specialized care.

Bengal Physician JournalVol. 13(2)
Gender equality
Openalex Percentile: Top 7%
Cutaneous lymphoproliferative disorders research
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