Polynuclear silver complexes in modern chemistry: synthesis, structure, emerging applications and future perspective

Abstract Polynuclear silver complexes (PNSCs), formed through the coordination of multiple silver ions, constitute a structurally diverse class of compounds with broad scientific relevance. In this review, PNSCs synthesis methods, challenges faced in the synthesis and their possible solution are discussed. Furthermore, key structural features and factors that strongly influenced the geometry and diversity of the complexes are described in detail; particular attention is given to ligand nature, solvent nature, counter-ions, and thermodynamic parameters. To highlight their emerging biomedical applications, a wide range of biological activities such as antimicrobial, anticancer, and wound-healing are depicted in the manuscript. Besides, practices in catalysis and hydrogen storage are also explained to explore their role in material science. Lastly, to expedite future research on PNSCs, potential future directions have been given for further exploration. The knowledge gained through this review will not only advance understanding of the chemistry of PNSCs’ but also underscore their importance in both health-related and materials research.