Clinicopathologic spectrum and outcomes analysis of Meckel’s diverticulum in children

Introduction : Meckel’s diverticulum is the most common congenital anomaly of the gastrointestinal system. Although often asymptomatic, it can present with a wide range of complications in children. Early diagnosis remains challenging due to nonspecific symptoms and the limited sensitivity of imaging modalities. Aim : This study aims to evaluate the spectrum of clinical presentations, diagnostic approaches, surgical management, and histopathological outcomes in a pediatric population with Meckel’s diverticulum. Materials and methods : This prospective cross-section observational study was carried at a tertiary care center from November 2021 to October 2025. All children under 18 years diagnosed with Meckel’s diverticulum either symptomatically or incidentally during surgery were included. Data on demographics, clinical presentation, diagnostic modalities, surgical approach, postoperative outcomes, and histopathological findings were analyzed. Results : A total of 28 children were surgically treated for Meckel’s diverticulum. Male predominance was noted (71.43%), with the most affected age group being 1–5 years (42.86%). Intestinal obstruction (28.57%) was the most common presentation, followed by intussusception (21.43%) and perforation (17.86%). All patients underwent laparoscopic-assisted segmental ileal resection. Postoperative complications were minimal (7.14%), and mean hospital stay was 5.6 days. Histopathology revealed ectopic mucosa in 67.86% of cases, predominantly gastric (57.14%), with pancreatic tissue in 11.3%. Ectopic tissue was most frequently associated with perforation (100%) and intussusception (83.3%) Conclusion : Meckel’s diverticulum in children presents with diverse clinical manifestations, often mimicking other acute abdominal conditions. Early surgical intervention, especially in symptomatic cases, yields favorable outcomes. The presence of ectopic mucosa correlates strongly with complications, underscoring the importance of segmental resection and routine histopathological evaluation.