Efficacy of Intraoperative Inhaled Nitric Oxide in Off-Pump Coronary Artery Bypass Grafting in Patients With Low Ejection Fraction
Background: One of the challenges with off-pump coronary artery bypass grafting (OPCAB) in patients with low left ventricular ejection fraction (LVEF) is the transient increase in right ventricular (RV) afterload during cardiac displacement. We developed the “iNO bundle,” a protocol integrating pulmonary artery catheter (PAC)-guided navigation with titrated inhaled nitric oxide (iNO), to stabilize hemodynamics.
Authors
- Hideaki Hidaka
- Kosaku Nishigawa (ORCID: https://orcid.org/0000-0002-6303-8431)
- Jun Takaki
- Toshihiro Fukui (ORCID: https://orcid.org/0000-0002-4110-6237)
- Kenyu Hashimoto (ORCID: https://orcid.org/0000-0001-9731-8290)
- Tatsuya Horibe (ORCID: https://orcid.org/0009-0002-2991-4095)
- Hiroki Nishiguchi
- Takashi Yoshinaga
- Takafumi Hirota
- Kazuki Uchikura
Institutions
- Kumamoto University Hospital (JP)
- Center for Clinical Research (United States) (US)
Publication Details
- Journal
- Circulation Reports
- Published
- 2026-06-30
- DOI
- https://doi.org/10.1253/circrep.cr-26-0154
- Primary Topic
- Cardiac and Coronary Surgery Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00