Artificial intelligence demonstrates comparable diagnostic accuracy to radiologists for anterior cruciate ligament tears on MRI: A systematic review and meta‐analysis

PURPOSE: Anterior cruciate ligament (ACL) tears are among the most common knee injuries, accounting for half of all knee ligament injuries. Magnetic resonance imaging (MRI) is the standard for diagnosing ACL tears, but its interpretation is experience-dependent. Artificial intelligence (AI), particularly deep learning (DL), has emerged as a transformative tool in medical imaging, offering advanced pattern recognition for detecting abnormalities. METHODS: This study systematically reviews and meta-analyses the diagnostic accuracy of AI in detecting ACL tears, comparing with radiologists' performance. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy Studies (PRISMA-DTA) guidelines, a comprehensive search of Embase, PubMed and Cochrane databases identified 247 articles, with 40 studies included in qualitative synthesis and 31 in meta-analysis, encompassing 1192 cases. RESULTS: In the overall pooled analysis, AI demonstrated a sensitivity of 0.94 (95% confidence interval [CI]: 0.93-0.95) and specificity of 0.93 (95% CI: 0.92-0.93). In the subgroup comparing AI directly to radiologists, AI demonstrated pooled sensitivity and specificity of 0.90 (95% CI: 0.88-0.92) and 0.91 (95% CI: 0.89-0.92), respectively, while radiologists showed 0.85 (95% CI: 0.83-0.87) and 0.90 (95% CI: 0.88-0.91). Heterogeneity varied, with moderate to high heterogeneity in the analyses. Summary receiver operating characteristic (sROC) analysis indicated no significant difference between AI and radiologists in diagnostic accuracy (p = 0.782). CONCLUSION: These findings suggest that AI can match human diagnostic performance for ACL tears, offering advantages such as reduced costs, faster results and decreased physician burden. Despite variability in study settings, AI shows promise as a reliable diagnostic tool in knee imaging. LEVEL OF EVIDENCE: Level II.

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Journal
Knee Surgery Sports Traumatology Arthroscopy
Published
2026-06-30
DOI
https://doi.org/10.1002/ksa.70478
Primary Topic
Knee injuries and reconstruction techniques
Type
article
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article

Artificial intelligence demonstrates comparable diagnostic accuracy to radiologists for anterior cruciate ligament tears on MRI: A systematic review and meta‐analysis

Nacime Salomão Barbachan Mansur, Chilan Bou Ghosson Leite, Giovanna Medina, Gabriel Moraes de Oliveira et al.
Knee Surgery Sports Traumatology Arthroscopy
Knee injuries and reconstruction techniques
article

Artificial intelligence demonstrates comparable diagnostic accuracy to radiologists for anterior cruciate ligament tears on MRI: A systematic review and meta‐analysis

Nacime Salomão Barbachan Mansur, Chilan Bou Ghosson Leite, Giovanna Medina, Gabriel Moraes de Oliveira, Ana Beatriz Nardelli da Silva, António Almeida, Serafina F Zotter, Brian S. Tao, Maria mascarenhas
article en

Abstract

PURPOSE: Anterior cruciate ligament (ACL) tears are among the most common knee injuries, accounting for half of all knee ligament injuries. Magnetic resonance imaging (MRI) is the standard for diagnosing ACL tears, but its interpretation is experience-dependent. Artificial intelligence (AI), particularly deep learning (DL), has emerged as a transformative tool in medical imaging, offering advanced pattern recognition for detecting abnormalities. METHODS: This study systematically reviews and meta-analyses the diagnostic accuracy of AI in detecting ACL tears, comparing with radiologists' performance. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy Studies (PRISMA-DTA) guidelines, a comprehensive search of Embase, PubMed and Cochrane databases identified 247 articles, with 40 studies included in qualitative synthesis and 31 in meta-analysis, encompassing 1192 cases. RESULTS: In the overall pooled analysis, AI demonstrated a sensitivity of 0.94 (95% confidence interval [CI]: 0.93-0.95) and specificity of 0.93 (95% CI: 0.92-0.93). In the subgroup comparing AI directly to radiologists, AI demonstrated pooled sensitivity and specificity of 0.90 (95% CI: 0.88-0.92) and 0.91 (95% CI: 0.89-0.92), respectively, while radiologists showed 0.85 (95% CI: 0.83-0.87) and 0.90 (95% CI: 0.88-0.91). Heterogeneity varied, with moderate to high heterogeneity in the analyses. Summary receiver operating characteristic (sROC) analysis indicated no significant difference between AI and radiologists in diagnostic accuracy (p = 0.782). CONCLUSION: These findings suggest that AI can match human diagnostic performance for ACL tears, offering advantages such as reduced costs, faster results and decreased physician burden. Despite variability in study settings, AI shows promise as a reliable diagnostic tool in knee imaging. LEVEL OF EVIDENCE: Level II.

Knee Surgery Sports Traumatology Arthroscopy
Boston University (US), Brigham and Women's Hospital (US), Harvard University (US), University of Bradford (GB), Universidade Federal de Sergipe (BR), MedStar Union Memorial Hospital (US), Massachusetts General Hospital (US), Faculdade de Ciências Médicas da Santa Casa de São Paulo (BR), Universidade Federal de São Paulo (BR)
Openalex Percentile: Top 7%
Knee injuries and reconstruction techniques
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