Fenbendazole-Associated Drug-Induced Liver Injury with Concomitant Use of Tauroursodeoxycholic Acid

Influenced by the internet and social media, a growing number of individuals are taking hepatotoxic amounts of prescription and nonprescription drugs leading to drug-induced liver injuries (DILIs). We present a case of fenbendazole-associated DILI with concomitant use of tauroursodeoxycholic acid as an intended hepatoprotective agent. While fenbendazole-associated DILI has been increasingly reported, this case is unique due to associated tauroursodeoxycholic acid use, and, to our knowledge, represents the first published report of this exposure combination. This case builds on the growing literature of DILI due to nonprescription drugs and highlights the importance of patient-centered counseling.

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Publication Details

Journal
ACG Case Reports Journal
Published
2026-06-30
DOI
https://doi.org/10.14309/crj.0000000000002222
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
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article

Fenbendazole-Associated Drug-Induced Liver Injury with Concomitant Use of Tauroursodeoxycholic Acid

Brian Sasso, Alexander Satinsky, Nancy Mayer, Charles Swanson
ACG Case Reports Journal
Drug-Induced Hepatotoxicity and Protection
article

Fenbendazole-Associated Drug-Induced Liver Injury with Concomitant Use of Tauroursodeoxycholic Acid

Brian Sasso, Alexander Satinsky, Nancy Mayer, Charles Swanson
article en

Abstract

Influenced by the internet and social media, a growing number of individuals are taking hepatotoxic amounts of prescription and nonprescription drugs leading to drug-induced liver injuries (DILIs). We present a case of fenbendazole-associated DILI with concomitant use of tauroursodeoxycholic acid as an intended hepatoprotective agent. While fenbendazole-associated DILI has been increasingly reported, this case is unique due to associated tauroursodeoxycholic acid use, and, to our knowledge, represents the first published report of this exposure combination. This case builds on the growing literature of DILI due to nonprescription drugs and highlights the importance of patient-centered counseling.

ACG Case Reports JournalVol. 13(7)
Olivet Nazarene University (US)
Good health and well-being
Openalex Percentile: Top 8%
Drug-Induced Hepatotoxicity and Protection
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