Hyperbaric Oxygen Treatment for Arterial Gas Embolism With Transient Cortical Blindness Following Intravenous Ozone Therapy: A Case Report.

Introduction: Cerebral arterial gas embolism (CAGE) is a rare but potentially fatal condition that can occur when air enters the arterial circulation. Case Report: This case report describes a 64-year-old female patient who experienced a sudden onset of left lower extremity weakness and bilateral vision loss following a session of intravenous ozone therapy. Initial diagnostic imaging did not reveal any acute abnormalities. However, her clinical presentation was consistent with CAGE. She was initially administered emergent hyperbaric oxygen (HBO₂) at 2.8 ATA, followed by additional sessions at 2.0 ATA, which led to progressive symptomatic improvement and full resolution of her visual and motor deficits. Discussion: This case highlights the importance of recognizing the potential complications of intravenous ozone therapy, including CAGE. Hyperbaric oxygen treatment should be considered an option for patients with AGE following this procedure.