TAF15-mediated m5C modification of MTHFD2 RNA reveals a novel therapeutic target for IDH mutant gliomas

Authors

Fufang Qiu
Jinsen Zhang (ORCID: https://orcid.org/0000-0003-1564-053X)
Minfeng Shu (ORCID: https://orcid.org/0000-0003-0514-1892)
Li Zhang (ORCID: https://orcid.org/0000-0001-8142-403X)
Xi Chen (ORCID: https://orcid.org/0009-0005-2765-6653)
Chunming Sun
Xiaoyu Wang
Peter JihCheng Wong
Wei Hua
Zhen Fan
Minjie Fu
Yuan Feng
Ruixin Wu

Institutions

Shanghai Medical College of Fudan University (CN)
Fudan University (CN)
University Town of Shenzhen (CN)
Shanghai Public Health Clinical Center (CN)
National Institute of Neurological Disorders and Stroke (US)
Shanghai Clinical Research Center (CN)
Huashan Hospital (CN)
Shanghai Center for Brain Science and Brain-Inspired Technology (CN)

Publication Details

Journal: Biomarker Research
Published: 2026-06-29
DOI: https://doi.org/10.1186/s40364-026-00962-8
Primary Topic: RNA modifications and cancer
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Natural Science Foundation of China

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article

TAF15-mediated m5C modification of MTHFD2 RNA reveals a novel therapeutic target for IDH mutant gliomas

Fufang Qiu, Jinsen Zhang, Minfeng Shu, Li Zhang et al.

Jun 29, 2026

Biomarker Research

RNA modifications and cancer

article

TAF15-mediated m5C modification of MTHFD2 RNA reveals a novel therapeutic target for IDH mutant gliomas

Fufang Qiu, Jinsen Zhang, Minfeng Shu, Li Zhang, Xi Chen, Chunming Sun, Xiaoyu Wang, Peter JihCheng Wong, Wei Hua, Zhen Fan, Minjie Fu, Yuan Feng, Ruixin Wu

June 29, 2026article en

Abstract

No abstract available for this paper.

Biomarker Research

Shanghai Medical College of Fudan University (CN), Fudan University (CN), University Town of Shenzhen (CN), Shanghai Public Health Clinical Center (CN), National Institute of Neurological Disorders and Stroke (US), Shanghai Clinical Research Center (CN), Huashan Hospital (CN), Shanghai Center for Brain Science and Brain-Inspired Technology (CN)

National Natural Science Foundation of China

Good health and well-being

Openalex Percentile: Top 11%

RNA modifications and cancer

DOI Open Access PDF OpenAlex

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TAF15-mediated m5C modification of MTHFD2 RNA reveals a novel therapeutic target for IDH mutant gliomas — Fufang Qiu, Jinsen Zhang, et al. · Biomarker Research (2026) | TGRS Research Map | TGRS