The Relationship Between Albumin, Uric Acid, and Uric Acid/Albumin Ratio and the Severity of Hypoxaemia in Patients with Chronic Obstructive Pulmonary Disease During Acute Exacerbation Periods

ObjectiveStudies in patients with chronic obstructive pulmonary disease have demonstrated an association with serum uric acid levels. In this study, we aimed to evaluate whether uric acid and uric acid/albumin levels could be used as predictors of disease severity in and execerbation COPD patients according to COPD stages and between COPD and healthy individuals.Material and MethodThis study included patients with COPD and healthy controls. Serum uric acid levels and uric acid/albumin ratios were assessed in each group, and their correlations with study parameters were investigated.ResultsA total of 141 individuals were included in our study; 103 of these were COPD patients (87 men and 16 women) with a mean age of 65.60 ± 9.17, and 38 were healthy controls. When comparing mild and moderate COPD (GOLD1, GOLD2) with severe and profound COPD (GOLD3, GOLD4), CRP levels and annual exacerbation numbers were statistically significantly higher in the advanced COPD group (p