Engineering hematopoietic stem and progenitor cells to generate red blood cells as viral traps against HIV-1.
. In sum, this work presents a potential strategy for the one-time delivery of CD4-RBC viral traps through autologous transplantation of engineered HSPCs.
Authors
- Matthew H. Porteus (ORCID: https://orcid.org/0000-0002-3850-4648)
- Freja K. Ekman (ORCID: https://orcid.org/0000-0003-3935-4685)
- William N. Feist (ORCID: https://orcid.org/0000-0002-5870-4460)
- Hana Y. Ghanim (ORCID: https://orcid.org/0000-0002-4102-2367)
- Kathleen Romero (ORCID: https://orcid.org/0000-0001-9917-2870)
- Kaya Ben-Efraim
- Sofia E. Luna (ORCID: https://orcid.org/0000-0002-9173-9518)
- Nelson A. Amorin
- Nicole M. Johnston
- Vivien Sheehan
- Megan Merritt-Garza
- Alex Pendergast
- Zak Kostamo
- Amanda M Dudek
- Britney Hernandez-Naughton
Institutions
- University of Iowa (US)
- Emory University (US)
- Center for Cancer and Blood Disorders (US)
- Children's Healthcare of Atlanta (US)
- Stanford University (US)
Publication Details
- Journal
- PubMed
- Published
- 2026-09-10
- DOI
- https://doi.org/10.1016/j.omta.2026.201799
- Primary Topic
- Erythrocyte Function and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00