The Role of p-VEGFR2/p-AKT and HDAC1 in Apatinib-associated Inhibition of Gallbladder Cancer Cell Growth

Apatinib has been shown to be efficacious in the treatment of gallbladder cancer. However, the underlying mechanisms remain unclear. This study aimed to explore pathways related to the antitumor effects of apatinib at the cellular level in gallbladder cancer.

Authors

Publication Details

Journal
Exploratory Research and Hypothesis in Medicine
Published
2026-06-29
DOI
https://doi.org/10.14218/erhm.2025.00077
Primary Topic
Histone Deacetylase Inhibitors Research
Type
article
Field-Weighted Citation Impact
0.00

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article

The Role of p-VEGFR2/p-AKT and HDAC1 in Apatinib-associated Inhibition of Gallbladder Cancer Cell Growth

Yichong Ning, Luting Wang, Yingde Nong, Wei Huang et al.
Exploratory Research and Hypothesis in Medicine
Histone Deacetylase Inhibitors Research
article

The Role of p-VEGFR2/p-AKT and HDAC1 in Apatinib-associated Inhibition of Gallbladder Cancer Cell Growth

Yichong Ning, Luting Wang, Yingde Nong, Wei Huang, Yanmin Pang, Kai Xiao, Liang’e Xia, Wenmei Zhao
article en

Abstract

Apatinib has been shown to be efficacious in the treatment of gallbladder cancer. However, the underlying mechanisms remain unclear. This study aimed to explore pathways related to the antitumor effects of apatinib at the cellular level in gallbladder cancer.

Exploratory Research and Hypothesis in MedicineVol. 11(3)
Hunan Normal University, Natural Science Foundation of Hunan Province
Good health and well-being
Openalex Percentile: Top 11%
Histone Deacetylase Inhibitors Research
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